Resting state functional atlas and cerebral networks in mouse lemur primates at 11.7 Tesla
Copyright © 2020. Published by Elsevier Inc..
Measures of resting-state functional connectivity allow the description of neuronal networks in humans and provide a window on brain function in normal and pathological conditions. Characterizing neuronal networks in animals is complementary to studies in humans to understand how evolution has modelled network architecture. The mouse lemur (Microcebus murinus) is one of the smallest and more phylogenetically distant primates as compared to humans. Characterizing the functional organization of its brain is critical for scientists studying this primate as well as to add a link for comparative animal studies. Here, we created the first functional atlas of mouse lemur brain and describe for the first time its cerebral networks. They were classified as two primary cortical networks (somato-motor and visual), two high-level cortical networks (fronto-parietal and fronto-temporal) and two limbic networks (sensory-limbic and evaluative-limbic). Comparison of mouse lemur and human networks revealed similarities between mouse lemur high-level cortical networks and human networks as the dorsal attentional (DAN), executive control (ECN), and default-mode networks (DMN). These networks were however not homologous, possibly reflecting differential organization of high-level networks. Finally, cerebral hubs were evaluated. They were grouped along an antero-posterior axis in lemurs while they were split into parietal and frontal clusters in humans.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2021 |
|---|---|
| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:226 |
|---|---|
| Enthalten in: |
NeuroImage - 226(2021) vom: 01. Feb., Seite 117589 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Garin, Clément M [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Brain function |
|---|
| Anmerkungen: |
Date Completed 09.03.2021 Date Revised 09.03.2021 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.neuroimage.2020.117589 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM318146703 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM318146703 | ||
| 003 | DE-627 | ||
| 005 | 20231225164739.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2021 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.neuroimage.2020.117589 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1060.xml |
| 035 | |a (DE-627)NLM318146703 | ||
| 035 | |a (NLM)33248260 | ||
| 035 | |a (PII)S1053-8119(20)31074-0 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Garin, Clément M |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Resting state functional atlas and cerebral networks in mouse lemur primates at 11.7 Tesla |
| 264 | 1 | |c 2021 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 09.03.2021 | ||
| 500 | |a Date Revised 09.03.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2020. Published by Elsevier Inc. | ||
| 520 | |a Measures of resting-state functional connectivity allow the description of neuronal networks in humans and provide a window on brain function in normal and pathological conditions. Characterizing neuronal networks in animals is complementary to studies in humans to understand how evolution has modelled network architecture. The mouse lemur (Microcebus murinus) is one of the smallest and more phylogenetically distant primates as compared to humans. Characterizing the functional organization of its brain is critical for scientists studying this primate as well as to add a link for comparative animal studies. Here, we created the first functional atlas of mouse lemur brain and describe for the first time its cerebral networks. They were classified as two primary cortical networks (somato-motor and visual), two high-level cortical networks (fronto-parietal and fronto-temporal) and two limbic networks (sensory-limbic and evaluative-limbic). Comparison of mouse lemur and human networks revealed similarities between mouse lemur high-level cortical networks and human networks as the dorsal attentional (DAN), executive control (ECN), and default-mode networks (DMN). These networks were however not homologous, possibly reflecting differential organization of high-level networks. Finally, cerebral hubs were evaluated. They were grouped along an antero-posterior axis in lemurs while they were split into parietal and frontal clusters in humans | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Brain function | |
| 650 | 4 | |a Cerebral networks | |
| 650 | 4 | |a Functional MRI | |
| 650 | 4 | |a Hubs | |
| 650 | 4 | |a Microcebus murinus | |
| 650 | 4 | |a Mouse lemur atlas | |
| 650 | 4 | |a Resting state | |
| 700 | 1 | |a Nadkarni, Nachiket A |e verfasserin |4 aut | |
| 700 | 1 | |a Landeau, Brigitte |e verfasserin |4 aut | |
| 700 | 1 | |a Chételat, Gaël |e verfasserin |4 aut | |
| 700 | 1 | |a Picq, Jean-Luc |e verfasserin |4 aut | |
| 700 | 1 | |a Bougacha, Salma |e verfasserin |4 aut | |
| 700 | 1 | |a Dhenain, Marc |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t NeuroImage |d 1992 |g 226(2021) vom: 01. Feb., Seite 117589 |w (DE-627)NLM09001443X |x 1095-9572 |7 nnns |
| 773 | 1 | 8 | |g volume:226 |g year:2021 |g day:01 |g month:02 |g pages:117589 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.neuroimage.2020.117589 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 226 |j 2021 |b 01 |c 02 |h 117589 | ||