A rapid review and synthesis of the effectiveness of programmes initiating community-based antiretroviral therapy in sub-Saharan Africa
© 2020. The Authors..
BACKGROUND: Community-based antiretroviral therapy initiation (CB-ARTi) has the potential to reduce attrition by increasing access to care, reducing patient costs, decongesting clinics and ensuring improved uptake of ART. There is a paucity of research that identifies successful implementation of CB-ARTi in sub-Saharan Africa (SSA).
OBJECTIVES: The aim of the study was to review and describe the evidence on the effectiveness of CB-ARTi programmes that start ART in communities in comparison with the current standards of care in SSA.
METHODS: A rapid review of grey and published peer-reviewed literature between January 2009 and July 2019, by using PubMed, PDQ-Evidence, Google Scholar, clinical trial databases and major HIV (human immunodeficiency virus) conference websites, was conducted. Search terms used included 'community-based', 'home initiation community models', 'antiretroviral therapy', 'clinical outcomes', 'viral suppression', 'retention in care', 'loss to follow-up', 'HIV' and 'sub-Saharan Africa'.
RESULTS: The search yielded 90 articles and reports following the removal of duplicates. After initial screening and full-text screening, six articles remained and were included in the qualitative narrative synthesis. This included four randomised control trials and two cohort studies of specific interventions comparing CB-ARTi with the standard of care in SSA. There is evidence that CB-ARTi can increase access to HIV-testing services, linkage to ART, retention in care and viral suppression rates and is possibly not inferior to facility-based healthcare.
CONCLUSION: CB-ARTi has the potential to increase access to HIV services to people living with HIV in SSA. The results mentioned previously suggest that CB-ARTi models could prove to be equal and possibly not inferior to facility-based ones and warrant further investigation.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:21 |
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| Enthalten in: |
Southern African journal of HIV medicine - 21(2020), 1 vom: 03., Seite 1153 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Chimatira, Raymond [VerfasserIn] |
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| Links: |
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| Themen: |
ART initiation |
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| Anmerkungen: |
Date Revised 18.04.2022 published: Electronic-eCollection Citation Status PubMed-not-MEDLINE |
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| doi: |
10.4102/sajhivmed.v21i1.1153 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM318071169 |
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| 100 | 1 | |a Chimatira, Raymond |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A rapid review and synthesis of the effectiveness of programmes initiating community-based antiretroviral therapy in sub-Saharan Africa |
| 264 | 1 | |c 2020 | |
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| 500 | |a Date Revised 18.04.2022 | ||
| 500 | |a published: Electronic-eCollection | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a © 2020. The Authors. | ||
| 520 | |a BACKGROUND: Community-based antiretroviral therapy initiation (CB-ARTi) has the potential to reduce attrition by increasing access to care, reducing patient costs, decongesting clinics and ensuring improved uptake of ART. There is a paucity of research that identifies successful implementation of CB-ARTi in sub-Saharan Africa (SSA) | ||
| 520 | |a OBJECTIVES: The aim of the study was to review and describe the evidence on the effectiveness of CB-ARTi programmes that start ART in communities in comparison with the current standards of care in SSA | ||
| 520 | |a METHODS: A rapid review of grey and published peer-reviewed literature between January 2009 and July 2019, by using PubMed, PDQ-Evidence, Google Scholar, clinical trial databases and major HIV (human immunodeficiency virus) conference websites, was conducted. Search terms used included 'community-based', 'home initiation community models', 'antiretroviral therapy', 'clinical outcomes', 'viral suppression', 'retention in care', 'loss to follow-up', 'HIV' and 'sub-Saharan Africa' | ||
| 520 | |a RESULTS: The search yielded 90 articles and reports following the removal of duplicates. After initial screening and full-text screening, six articles remained and were included in the qualitative narrative synthesis. This included four randomised control trials and two cohort studies of specific interventions comparing CB-ARTi with the standard of care in SSA. There is evidence that CB-ARTi can increase access to HIV-testing services, linkage to ART, retention in care and viral suppression rates and is possibly not inferior to facility-based healthcare | ||
| 520 | |a CONCLUSION: CB-ARTi has the potential to increase access to HIV services to people living with HIV in SSA. The results mentioned previously suggest that CB-ARTi models could prove to be equal and possibly not inferior to facility-based ones and warrant further investigation | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a ART initiation | |
| 650 | 4 | |a HIV | |
| 650 | 4 | |a attrition | |
| 650 | 4 | |a community-based ART | |
| 650 | 4 | |a interventions | |
| 650 | 4 | |a retention | |
| 650 | 4 | |a sub-Saharan Africa | |
| 650 | 4 | |a viral suppression | |
| 700 | 1 | |a Ross, Andrew |e verfasserin |4 aut | |
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