Chemistry and Biology of Natural Azoxy Compounds

Azoxy compounds belong to a small yet intriguing group of natural products sharing a common functional group with the general structure RN═N+(O-)R. Their intriguing chemical structures, diverse biological activities, and important industrial applications have received attention from researchers in natural product chemistry, total synthesis, and biosynthesis. This review presents current updates about the structural diversity of natural azoxy compounds isolated from different organisms and highlights the enzymes and biological logic involved in their construction. We assume that the identification of key enzymes will provide efficient tools in biocatalysis to generate new azoxy compounds, while genome mining may result in novel natural azoxy compounds of medical and industrial interest.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:83

Enthalten in:

Journal of natural products - 83(2020), 11 vom: 25. Nov., Seite 3482-3491

Sprache:

Englisch

Beteiligte Personen:

Wibowo, Mario [VerfasserIn]
Ding, Ling [VerfasserIn]

Links:

Volltext

Themen:

Azo Compounds
Biological Products
Journal Article
Research Support, Non-U.S. Gov't
Review

Anmerkungen:

Date Completed 27.10.2021

Date Revised 27.10.2021

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1021/acs.jnatprod.0c00725

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM317645617