Development of magnetic dispersive micro-solid phase extraction based on magnetic agarose nanoparticles and deep eutectic solvents for the isolation and pre-concentration of three flavonoids in edible natural samples
Copyright © 2020 Elsevier B.V. All rights reserved..
In the present study, an environmentally friendly magnetic dispersive micro-solid phase extraction was developed based on magnetic agarose nanoparticles and deep eutectic solvents for the isolation and pre-concentration of three flavonoids (morin, quercetin, and kaempferol) from dark tea, chocolate, vegetable, and fruit juice samples. In this method, deep eutectic solvents were synthesized from less toxic and low-cost substances under feasible conditions and used as eluents in the desorption process. These solvents can be considered as a green alternative to traditional organic reagents to increase the adsorption capacity and reduce the matrix interferences, dangerous waste generation and environmental pollution. A Plackett-Burman design was employed for screening the experimental variables. The effective variables were then optimized by Box-Behnken design (BBD). Under the optimial conditions, the presented method demonstrated wide linear ranges of 1-500 μg. L-1 for morin and quercetin, and 5-500 μg. L-1 for kaempferol with satisfactory recoveries above 91%. Limit of detections (LODs) and quantifications (LOQs) of flavonoids varied in 0.2-1.1 μg. L-1 and 0.66-3.63 μg. L-1, respectively. The precision of the proposed method was the range of 2.6-5.7%.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:222 |
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| Enthalten in: |
Talanta - 222(2021) vom: 15. Jan., Seite 121649 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Majidi, Seyedeh Maedeh [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 14.05.2021 Date Revised 14.05.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.talanta.2020.121649 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM31735020X |
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| 520 | |a Copyright © 2020 Elsevier B.V. All rights reserved. | ||
| 520 | |a In the present study, an environmentally friendly magnetic dispersive micro-solid phase extraction was developed based on magnetic agarose nanoparticles and deep eutectic solvents for the isolation and pre-concentration of three flavonoids (morin, quercetin, and kaempferol) from dark tea, chocolate, vegetable, and fruit juice samples. In this method, deep eutectic solvents were synthesized from less toxic and low-cost substances under feasible conditions and used as eluents in the desorption process. These solvents can be considered as a green alternative to traditional organic reagents to increase the adsorption capacity and reduce the matrix interferences, dangerous waste generation and environmental pollution. A Plackett-Burman design was employed for screening the experimental variables. The effective variables were then optimized by Box-Behnken design (BBD). Under the optimial conditions, the presented method demonstrated wide linear ranges of 1-500 μg. L-1 for morin and quercetin, and 5-500 μg. L-1 for kaempferol with satisfactory recoveries above 91%. Limit of detections (LODs) and quantifications (LOQs) of flavonoids varied in 0.2-1.1 μg. L-1 and 0.66-3.63 μg. L-1, respectively. The precision of the proposed method was the range of 2.6-5.7% | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Deep eutectic solvents | |
| 650 | 4 | |a Flavonoids | |
| 650 | 4 | |a High-performance liquid chromatography | |
| 650 | 4 | |a Magnetic agarose nanoparticles | |
| 650 | 4 | |a Magnetic dispersive micro-solid phase extraction | |
| 650 | 4 | |a Response surface methodology | |
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| 650 | 7 | |a Solvents |2 NLM | |
| 650 | 7 | |a Sepharose |2 NLM | |
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| 700 | 1 | |a Hadjmohammadi, Mohammad Reza |e verfasserin |4 aut | |
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