Indoor Microbial Exposures and Chronic Lung Disease : From Microbial Toxins to the Microbiome
Copyright © 2020 Elsevier Inc. All rights reserved..
Effects of environmental microbial exposures on human health have long been of interest. Microbes were historically assumed to be harmful, but data have suggested that microbial exposures can modulate the immune system. We focus on the effects of indoor environmental microbial exposure on chronic lung diseases. We found contradictory data in bacterial studies using endotoxin as a surrogate for bacterial exposure. Contradictory data also exist in studies of fungal exposure. Many factors may modulate the effect of environmental microbial exposures on lung health, including coexposures. Future studies need to clarify which method of assessing environmental microbial exposures is most relevant.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:41 |
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| Enthalten in: |
Clinics in chest medicine - 41(2020), 4 vom: 15. Dez., Seite 777-796 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Wolf, Molly [VerfasserIn] |
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| Links: |
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| Themen: |
Asthma |
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| Anmerkungen: |
Date Completed 12.02.2021 Date Revised 03.12.2021 published: Print Citation Status MEDLINE |
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| doi: |
10.1016/j.ccm.2020.08.005 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Effects of environmental microbial exposures on human health have long been of interest. Microbes were historically assumed to be harmful, but data have suggested that microbial exposures can modulate the immune system. We focus on the effects of indoor environmental microbial exposure on chronic lung diseases. We found contradictory data in bacterial studies using endotoxin as a surrogate for bacterial exposure. Contradictory data also exist in studies of fungal exposure. Many factors may modulate the effect of environmental microbial exposures on lung health, including coexposures. Future studies need to clarify which method of assessing environmental microbial exposures is most relevant | ||
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