Management of COVID-19 myopericarditis with reversal of cardiac dysfunction after blunting of cytokine storm : a case report

© The Author(s) 2020. Published by Oxford University Press on behalf of the European Society of Cardiology..

BACKGROUND: Coronavirus disease 2019 (COVID-19) is a syndrome that has been associated with multiple cardiac complications including myopericarditis. The pathophysiology and treatment for myopericarditis in the setting of COVID-19 infection is still under investigation.

CASE SUMMARY: We present a case of a 60-year-old male admitted for dyspnoea due to COVID-19. He developed new ST-segment elevation, elevated cardiac enzymes, severe left ventricular dysfunction, and high inflammatory markers in the setting of haemodynamic and respiratory collapse from the viral illness. He was diagnosed with COVID-19-induced myopericarditis. He showed rapid clinical improvement with a rapid wean off pressure support, resolution of electrocardiogram (ECG) findings, and recovery of left ventricular systolic function following treatment with intravenous immunoglobulin (IVIG) and methylprednisolone.

DISCUSSION: COVID-19's complex and devastating complications continue to create new challenges for clinicians. Cardiac complications, specifically, have been shown to be a signal for worse prognosis in these patients. IVIG and steroids can inhibit the inflammatory cascade and decrease myocardial injury, with implications in treatment of severe myopericarditis.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:4

Enthalten in:

European heart journal. Case reports - 4(2020), FI1 vom: 07. Okt., Seite 1-6

Sprache:

Englisch

Beteiligte Personen:

Li, Angela [VerfasserIn]
Garcia-Bengochea, Youssef [VerfasserIn]
Stechel, Richard [VerfasserIn]
Azari, Bani M [VerfasserIn]

Links:

Volltext

Themen:

COVID-19
Case Reports
Case report
Cytokine storm
IVIG
Myocarditis
Myopericarditis
Pericarditis

Anmerkungen:

Date Revised 12.11.2023

published: Electronic-eCollection

Citation Status PubMed-not-MEDLINE

doi:

10.1093/ehjcr/ytaa224

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM316580287