Functional links between sensory representations, choice activity, and sensorimotor associations in parietal cortex
© 2020, Chang et al..
Three-dimensional (3D) representations of the environment are often critical for selecting actions that achieve desired goals. The success of these goal-directed actions relies on 3D sensorimotor transformations that are experience-dependent. Here we investigated the relationships between the robustness of 3D visual representations, choice-related activity, and motor-related activity in parietal cortex. Macaque monkeys performed an eight-alternative 3D orientation discrimination task and a visually guided saccade task while we recorded from the caudal intraparietal area using laminar probes. We found that neurons with more robust 3D visual representations preferentially carried choice-related activity. Following the onset of choice-related activity, the robustness of the 3D representations further increased for those neurons. We additionally found that 3D orientation and saccade direction preferences aligned, particularly for neurons with choice-related activity, reflecting an experience-dependent sensorimotor association. These findings reveal previously unrecognized links between the fidelity of ecologically relevant object representations, choice-related activity, and motor-related activity.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:9 |
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| Enthalten in: |
eLife - 9(2020) vom: 20. Okt. |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Chang, Ting-Yu [VerfasserIn] |
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| Links: |
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| Themen: |
3D vision |
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| Anmerkungen: |
Date Completed 14.05.2021 Date Revised 01.02.2023 published: Electronic Citation Status MEDLINE |
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| doi: |
10.7554/eLife.57968 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM316480126 |
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| 520 | |a © 2020, Chang et al. | ||
| 520 | |a Three-dimensional (3D) representations of the environment are often critical for selecting actions that achieve desired goals. The success of these goal-directed actions relies on 3D sensorimotor transformations that are experience-dependent. Here we investigated the relationships between the robustness of 3D visual representations, choice-related activity, and motor-related activity in parietal cortex. Macaque monkeys performed an eight-alternative 3D orientation discrimination task and a visually guided saccade task while we recorded from the caudal intraparietal area using laminar probes. We found that neurons with more robust 3D visual representations preferentially carried choice-related activity. Following the onset of choice-related activity, the robustness of the 3D representations further increased for those neurons. We additionally found that 3D orientation and saccade direction preferences aligned, particularly for neurons with choice-related activity, reflecting an experience-dependent sensorimotor association. These findings reveal previously unrecognized links between the fidelity of ecologically relevant object representations, choice-related activity, and motor-related activity | ||
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| 650 | 4 | |a 3D vision | |
| 650 | 4 | |a choice activity | |
| 650 | 4 | |a neuroscience | |
| 650 | 4 | |a nuisance variables | |
| 650 | 4 | |a oculomotor | |
| 650 | 4 | |a parietal cortex | |
| 650 | 4 | |a rhesus macaque | |
| 650 | 4 | |a sensorimotor | |
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| 700 | 1 | |a Thompson, Lowell W |e verfasserin |4 aut | |
| 700 | 1 | |a Lowe, Meghan E |e verfasserin |4 aut | |
| 700 | 1 | |a Rosenberg, Ari |e verfasserin |4 aut | |
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