Pre-Stroke Depression in Ghana and Nigeria : Prevalence, Predictors and Association With Poststroke Depression

OBJECTIVES: Depression is a risk factor for stroke. There is a knowledge gap on the predictors of prestroke depression in stroke survivors living in low- and middle-income countries (LMICs). We estimated prevalence and predictors of prestroke depression, as well as its association with poststroke depression (PSD) in the largest study of stroke in Africa.

METHODS: We evaluated information collected as part of the Stroke Investigative Research and Education Network (SIREN) study, a multicentre, case-control study conducted at 15 sites in Ghana and Nigeria. Prestroke depression status was ascertained in stroke survivors using a validated self-report tool, while PSD was assessed using a stroke specific screening tool for depression ("HRQOLISP-E"). Independent associations were investigated using complementary log-log regression and binary logit models.

RESULTS: Among 1,977 participants, prestroke depression was found in 141 (7.1%). In multivariate analyses, prestroke depression was significantly associated with tachycardia (OR = 2.22, 95% CI = 1.37-3.56) and low consumption of green leafy vegetables (OR = 1.91, 95% CI = 1.12-3.24). Forty-one (29.1%) of the prestroke depression sub-sample developed PSD. However, prestroke depression was not significantly associated with PSD.

CONCLUSION: The findings should energize before-the-stroke identification and prioritization of limited treatment resources in LMICs to persons with depression who have multiple, additional, risks of stroke.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:35

Enthalten in:

Journal of geriatric psychiatry and neurology - 35(2022), 1 vom: 01. Jan., Seite 121-127

Sprache:

Englisch

Beteiligte Personen:

Ojagbemi, Akin [VerfasserIn]
Akinyemi, Joshua [VerfasserIn]
Wahab, Kolawole [VerfasserIn]
Owolabi, Lukman [VerfasserIn]
Arulogun, Oyedunni [VerfasserIn]
Akpalu, Josephine [VerfasserIn]
Akpalu, Albert [VerfasserIn]
Ogbole, Godwin [VerfasserIn]
Akinsanya, Cynthia [VerfasserIn]
Wasiu, Adeniyi [VerfasserIn]
Tito-Ilori, Moyinoluwa [VerfasserIn]
Adekunle, Fakunle [VerfasserIn]
Lyrea, Ruth [VerfasserIn]
Akpa, Onoja [VerfasserIn]
Akinyemi, Rufus [VerfasserIn]
Sarfo, Fred [VerfasserIn]
Owolabi, Mayowa [VerfasserIn]
Ovbiagele, Bruce [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Mental health complications
Multicenter Study
Prestroke symptoms
Research Support, N.I.H., Extramural
Stroke burden
Stroke risk factors
Sub-Saharan Africa

Anmerkungen:

Date Completed 26.01.2022

Date Revised 02.01.2023

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1177/0891988720968274

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM316431125