Synthesis of dopamine-derived N-doped carbon nanotubes/Fe3O4 composites as enhanced electrochemical sensing platforms for hydrogen peroxide detection
A novel preparation of dopamine-derived N-doped carbon nanotubes/Fe3O4 composites (N-CNTs/Fe3O4 Cs) is demonstrated via facile hydrothermal route and calcination treatment. In this approach, dopamine was selected as N-containing precursor, which can promote Fe3O4 nanocrystal deposition uniformly on the surface of CNTs and effectively modulated the graphitic structure with doped pyridinic N and graphitic N to improve the electrochemical performance of carbon composites. More interestingly, the inhibited growth of the Fe3O4 crystal during calcination can be effectively avoided by soaking PDA-CNT/Fe3O4 Cs in a phosphate solution before calcination. The N-CNTs/Fe3O4 Cs have an enhanced electrocatalytic activity toward hydrogen peroxide with high sensitivity (316.27 mA M-1 cm-2) and wide linear range (0.006-2.057 mM). The N-CNTs/Fe3O4 Cs modified sensor was successfully applied to real-time detection of H2O2 released from living cancer cells, displaying a potential application in the study of oxidative stress-related diseases. This work demonstrates a rational way for high-performance electrocatalytic material synthesis and bioanalysis. Graphical abstract An enzyme-free biosensor of H2O2 was constructed on the basis of dopamine-derived N-doped carbon nanotubes/Fe3O4 composites (N-CNTs/Fe3O4 Cs), and it exhibited the enhanced electrocatalytic activity for H2O2 detection with high sensitivity, wide linear range, and outstanding reproducibility and stability.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:187 |
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| Enthalten in: |
Mikrochimica acta - 187(2020), 11 vom: 13. Okt., Seite 605 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Zhao, Yanan [VerfasserIn] |
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| Links: |
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| Themen: |
Cancer cell H2O2 release |
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| Anmerkungen: |
Date Completed 13.08.2021 Date Revised 13.08.2021 published: Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1007/s00604-020-04575-2 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM316179256 |
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| 245 | 1 | 0 | |a Synthesis of dopamine-derived N-doped carbon nanotubes/Fe3O4 composites as enhanced electrochemical sensing platforms for hydrogen peroxide detection |
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| 500 | |a Date Revised 13.08.2021 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a A novel preparation of dopamine-derived N-doped carbon nanotubes/Fe3O4 composites (N-CNTs/Fe3O4 Cs) is demonstrated via facile hydrothermal route and calcination treatment. In this approach, dopamine was selected as N-containing precursor, which can promote Fe3O4 nanocrystal deposition uniformly on the surface of CNTs and effectively modulated the graphitic structure with doped pyridinic N and graphitic N to improve the electrochemical performance of carbon composites. More interestingly, the inhibited growth of the Fe3O4 crystal during calcination can be effectively avoided by soaking PDA-CNT/Fe3O4 Cs in a phosphate solution before calcination. The N-CNTs/Fe3O4 Cs have an enhanced electrocatalytic activity toward hydrogen peroxide with high sensitivity (316.27 mA M-1 cm-2) and wide linear range (0.006-2.057 mM). The N-CNTs/Fe3O4 Cs modified sensor was successfully applied to real-time detection of H2O2 released from living cancer cells, displaying a potential application in the study of oxidative stress-related diseases. This work demonstrates a rational way for high-performance electrocatalytic material synthesis and bioanalysis. Graphical abstract An enzyme-free biosensor of H2O2 was constructed on the basis of dopamine-derived N-doped carbon nanotubes/Fe3O4 composites (N-CNTs/Fe3O4 Cs), and it exhibited the enhanced electrocatalytic activity for H2O2 detection with high sensitivity, wide linear range, and outstanding reproducibility and stability | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Cancer cell H2O2 release | |
| 650 | 4 | |a Fe3O4 | |
| 650 | 4 | |a Hydrogen peroxide detection | |
| 650 | 4 | |a N-doped carbon nanotubes | |
| 650 | 4 | |a Polydopamine | |
| 700 | 1 | |a Huo, Danqun |e verfasserin |4 aut | |
| 700 | 1 | |a Jiang, Liuyi |e verfasserin |4 aut | |
| 700 | 1 | |a Zhou, Shiying |e verfasserin |4 aut | |
| 700 | 1 | |a Yang, Mei |e verfasserin |4 aut | |
| 700 | 1 | |a Hou, Changjun |e verfasserin |4 aut | |
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