Mouse Higher Visual Areas Provide Both Distributed and Specialized Contributions to Visually Guided Behaviors
Copyright © 2020 Elsevier Inc. All rights reserved..
Cortical parallel processing streams segregate many diverse features of a sensory scene. However, some features are distributed across streams, begging the question of whether and how such distributed representations contribute to perception. We determined the necessity of the primary visual cortex (V1) and three key higher visual areas (lateromedial [LM], anterolateral [AL], and posteromedial [PM]) for perception of orientation and contrast, two features that are robustly encoded across all four areas. Suppressing V1, LM, or AL decreased sensitivity for both orientation discrimination and contrast detection, consistent with a role for these areas in sensory perception. In comparison, suppressing PM selectively increased false alarm (FA) rates during contrast detection, without any effect on orientation discrimination. This effect was not retinotopically specific, suggesting that suppression of PM altered sensory integration or the decision-making process rather than processing of local visual features. Thus, we find that distributed representations in the visual system can nonetheless support specialized perceptual roles for higher visual cortical areas.
| Errataetall: |
CommentIn: Curr Biol. 2020 Dec 7;30(23):R1428-R1431. - PMID 33290711 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:30 |
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| Enthalten in: |
Current biology : CB - 30(2020), 23 vom: 07. Dez., Seite 4682-4692.e7 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Jin, Miaomiao [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Completed 23.08.2021 Date Revised 30.03.2024 published: Print-Electronic CommentIn: Curr Biol. 2020 Dec 7;30(23):R1428-R1431. - PMID 33290711 Citation Status MEDLINE |
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| doi: |
10.1016/j.cub.2020.09.015 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| 520 | |a Cortical parallel processing streams segregate many diverse features of a sensory scene. However, some features are distributed across streams, begging the question of whether and how such distributed representations contribute to perception. We determined the necessity of the primary visual cortex (V1) and three key higher visual areas (lateromedial [LM], anterolateral [AL], and posteromedial [PM]) for perception of orientation and contrast, two features that are robustly encoded across all four areas. Suppressing V1, LM, or AL decreased sensitivity for both orientation discrimination and contrast detection, consistent with a role for these areas in sensory perception. In comparison, suppressing PM selectively increased false alarm (FA) rates during contrast detection, without any effect on orientation discrimination. This effect was not retinotopically specific, suggesting that suppression of PM altered sensory integration or the decision-making process rather than processing of local visual features. Thus, we find that distributed representations in the visual system can nonetheless support specialized perceptual roles for higher visual cortical areas | ||
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