Antimicrobial susceptibility of Staphylococcus species isolated from prosthetic joints with a focus on fluoroquinolone-resistance mechanisms

Copyright © 2020. Published by Elsevier Inc..

We investigated susceptibility to antimicrobials of 89 staphylococcal species from PJIs and analyzed fluoroquinolone (FQ)-resistance mechanisms. Staphylococcal isolates showed high resistance to oral antimicrobials, with the exception of TMP-STX and linezolid. The main mechanism of resistance to FQ was mutations in quinolone-resistance-determining-regions. Fifteen percent of Staphylococcus aureus overexpressed efflux-pump genes.

Medienart:

E-Artikel

Erscheinungsjahr:

2021

Erschienen:

2021

Enthalten in:

Zur Gesamtaufnahme - volume:99

Enthalten in:

Diagnostic microbiology and infectious disease - 99(2021), 1 vom: 15. Jan., Seite 115173

Sprache:

Englisch

Beteiligte Personen:

Darboe, Kalifa Sanneh [VerfasserIn]
Oh, Tae-Hoon [VerfasserIn]
Choi, Su-Mi [VerfasserIn]
Kim, Hee-Kyung [VerfasserIn]
Kim, Seong Eun [VerfasserIn]
Kim, Uh Jin [VerfasserIn]
Kang, Seung-Ji [VerfasserIn]
Jang, Hee-Chang [VerfasserIn]
Jung, Sook-In [VerfasserIn]
Park, Kyung-Hwa [VerfasserIn]

Links:

Volltext

Themen:

133135-40-7
8064-90-2
Anti-Bacterial Agents
Bacterial Proteins
DNA Gyrase
DNA Topoisomerase IV
EC 5.99.1.-
EC 5.99.1.3
Fluoroquinolones
ISQ9I6J12J
Journal Article
Linezolid
Membrane Transport Proteins
Multidrug Resistance-Associated Proteins
Nor
NorA protein, Staphylococcus
Prosthetic joint infection
Quinolone resistance-determining region
Staphylococcus
Susceptibility
Trimethoprim, Sulfamethoxazole Drug Combination

Anmerkungen:

Date Completed 06.07.2021

Date Revised 06.07.2021

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.diagmicrobio.2020.115173

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM315627263