Antimicrobial susceptibility of Staphylococcus species isolated from prosthetic joints with a focus on fluoroquinolone-resistance mechanisms
Copyright © 2020. Published by Elsevier Inc..
We investigated susceptibility to antimicrobials of 89 staphylococcal species from PJIs and analyzed fluoroquinolone (FQ)-resistance mechanisms. Staphylococcal isolates showed high resistance to oral antimicrobials, with the exception of TMP-STX and linezolid. The main mechanism of resistance to FQ was mutations in quinolone-resistance-determining-regions. Fifteen percent of Staphylococcus aureus overexpressed efflux-pump genes.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2021 |
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Erschienen: |
2021 |
Enthalten in: |
Zur Gesamtaufnahme - volume:99 |
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Enthalten in: |
Diagnostic microbiology and infectious disease - 99(2021), 1 vom: 15. Jan., Seite 115173 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Darboe, Kalifa Sanneh [VerfasserIn] |
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Links: |
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Anmerkungen: |
Date Completed 06.07.2021 Date Revised 06.07.2021 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1016/j.diagmicrobio.2020.115173 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM315627263 |
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520 | |a We investigated susceptibility to antimicrobials of 89 staphylococcal species from PJIs and analyzed fluoroquinolone (FQ)-resistance mechanisms. Staphylococcal isolates showed high resistance to oral antimicrobials, with the exception of TMP-STX and linezolid. The main mechanism of resistance to FQ was mutations in quinolone-resistance-determining-regions. Fifteen percent of Staphylococcus aureus overexpressed efflux-pump genes | ||
650 | 4 | |a Journal Article | |
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700 | 1 | |a Jang, Hee-Chang |e verfasserin |4 aut | |
700 | 1 | |a Jung, Sook-In |e verfasserin |4 aut | |
700 | 1 | |a Park, Kyung-Hwa |e verfasserin |4 aut | |
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