Amplification-free profiling of microRNA-122 biomarker in DILI patient serums, using the luminex MAGPIX system
Copyright © 2020 Elsevier B.V. All rights reserved..
Dynamic chemical labelling is a single-base specific method to enable detection and quantification of micro-Ribonucleic Acids in biological fluids without extraction and pre-amplification. In this study, dynamic chemical labelling was combined with the Luminex MAGPIX system to profile levels of microRNA-122 biomarker in serum from patients with Drug-Induced Liver Injury.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:219 |
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| Enthalten in: |
Talanta - 219(2020) vom: 01. Nov., Seite 121265 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Marín-Romero, Antonio [VerfasserIn] |
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| Links: |
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| Themen: |
Biomarkers |
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| Anmerkungen: |
Date Completed 14.05.2021 Date Revised 14.05.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.talanta.2020.121265 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM314599800 |
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| 520 | |a Dynamic chemical labelling is a single-base specific method to enable detection and quantification of micro-Ribonucleic Acids in biological fluids without extraction and pre-amplification. In this study, dynamic chemical labelling was combined with the Luminex MAGPIX system to profile levels of microRNA-122 biomarker in serum from patients with Drug-Induced Liver Injury | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Drug-induced liver injury (DILI) | |
| 650 | 4 | |a Dynamic chemical labelling (DCL) | |
| 650 | 4 | |a Liquid biopsy | |
| 650 | 4 | |a Luminex MAGPIX | |
| 650 | 4 | |a miRNA-122 | |
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| 650 | 7 | |a MIRN122 microRNA, human |2 NLM | |
| 650 | 7 | |a MicroRNAs |2 NLM | |
| 700 | 1 | |a Tabraue-Chávez, Mavys |e verfasserin |4 aut | |
| 700 | 1 | |a Dear, James W |e verfasserin |4 aut | |
| 700 | 1 | |a Sánchez-Martín, Rosario M |e verfasserin |4 aut | |
| 700 | 1 | |a Ilyine, Hugh |e verfasserin |4 aut | |
| 700 | 1 | |a Guardia-Monteagudo, Juan J |e verfasserin |4 aut | |
| 700 | 1 | |a Fara, Mario A |e verfasserin |4 aut | |
| 700 | 1 | |a López-Delgado, Francisco J |e verfasserin |4 aut | |
| 700 | 1 | |a Díaz-Mochón, Juan J |e verfasserin |4 aut | |
| 700 | 1 | |a Pernagallo, Salvatore |e verfasserin |4 aut | |
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