Corticosteroids in the Management of Pregnant Patients With Coronavirus Disease (COVID-19)

Recent evidence supports the use of an early, short course of glucocorticoids in patients with COVID-19 who require mechanical ventilation or oxygen support. As the number of coronavirus disease 2019 (COVID-19) cases continues to increase, the number of pregnant women with the disease is very likely to increase as well. Because pregnant women are at increased risk for hospitalization, intensive care unit admission, and mechanical ventilation support, obstetricians will be facing the dilemma of initiating maternal corticosteroid therapy while weighing its potential adverse effects on the fetus (or neonate if the patient is postpartum and breastfeeding). Our objective is to summarize the current evidence supporting steroid therapy in the management of patients with acute respiratory distress syndrome and COVID-19 and to elaborate on key modifications for the pregnant patient.

Media Type:

Electronic Article

Year of Publication:

2020

Contained In:

Obstetrics and gynecology - Vol. 136, No. 4 (2020), p. 823-826

Language:

English

Contributors:

Saad, Antonio F
Chappell, Lucy
Saade, George R
Pacheco, Luis D

Links:

Volltext

Keywords:

*Coronavirus Infections
*Glucocorticoids
*Pandemics
*Pneumonia, Viral
*Pregnancy Complications, Infectious
Betacoronavirus
Critical Care
Drug Monitoring
Female
Fetal Organ Maturity
Glucocorticoids
Humans
Infant, Newborn
Journal Article
Medication Therapy Management
Oxygen Inhalation Therapy
Pregnancy
Respiration, Artificial
Risk Assessment

Notes:

Date Completed 05.10.2020

Date Revised 05.10.2020

published: Print

Citation Status MEDLINE

Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Physical Description:

Online-Ressource

doi:

10.1097/AOG.0000000000004103

PMID:

32769659

PPN (Catalogue-ID):

NLM314377727