Estimating the Effect of Depression on HIV Transmission Risk Behaviors Among People Who Inject Drugs in Vietnam : A Causal Approach
The burden of depression and HIV is high among people who inject drugs (PWID), yet the effect of depression on transmission risk behaviors is not well understood in this population. Using causal inference methods, we analyzed data from 455 PWID living with HIV in Vietnam 2009-2013. Study visits every 6 months over 2 years measured depressive symptoms in the past week and injecting and sexual behaviors in the prior 3 months. Severe depressive symptoms (vs. mild/no symptoms) increased injection equipment sharing (risk difference [RD] = 3.9 percentage points, 95% CI -1.7, 9.6) but not condomless sex (RD = -1.8, 95% CI -6.4, 2.8) as reported 6 months later. The cross-sectional association with injection equipment sharing at the same visit (RD = 6.2, 95% CI 1.4, 11.0) was stronger than the longitudinal effect. Interventions on depression among PWID may decrease sharing of injection equipment and the corresponding risk of HIV transmission.Clinical trial registration ClinicalTrials.gov NCT01689545.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:25 |
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| Enthalten in: |
AIDS and behavior - 25(2021), 2 vom: 24. Feb., Seite 438-446 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Levintow, Sara N [VerfasserIn] |
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| Links: |
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| Themen: |
Depressive symptoms |
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| Anmerkungen: |
Date Completed 12.02.2021 Date Revised 18.02.2022 published: Print ClinicalTrials.gov: NCT01689545 Citation Status MEDLINE |
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| doi: |
10.1007/s10461-020-03007-9 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM314066519 |
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| 500 | |a ClinicalTrials.gov: NCT01689545 | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The burden of depression and HIV is high among people who inject drugs (PWID), yet the effect of depression on transmission risk behaviors is not well understood in this population. Using causal inference methods, we analyzed data from 455 PWID living with HIV in Vietnam 2009-2013. Study visits every 6 months over 2 years measured depressive symptoms in the past week and injecting and sexual behaviors in the prior 3 months. Severe depressive symptoms (vs. mild/no symptoms) increased injection equipment sharing (risk difference [RD] = 3.9 percentage points, 95% CI -1.7, 9.6) but not condomless sex (RD = -1.8, 95% CI -6.4, 2.8) as reported 6 months later. The cross-sectional association with injection equipment sharing at the same visit (RD = 6.2, 95% CI 1.4, 11.0) was stronger than the longitudinal effect. Interventions on depression among PWID may decrease sharing of injection equipment and the corresponding risk of HIV transmission.Clinical trial registration ClinicalTrials.gov NCT01689545 | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Depressive symptoms | |
| 650 | 4 | |a HIV transmission | |
| 650 | 4 | |a Injecting behavior | |
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| 650 | 4 | |a People who inject drugs | |
| 650 | 4 | |a Sexual behavior | |
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| 700 | 1 | |a Ha, Tran Viet |e verfasserin |4 aut | |
| 700 | 1 | |a Chu, Viet Anh |e verfasserin |4 aut | |
| 700 | 1 | |a Quan, Vu Minh |e verfasserin |4 aut | |
| 700 | 1 | |a Latkin, Carl A |e verfasserin |4 aut | |
| 700 | 1 | |a Go, Vivian F |e verfasserin |4 aut | |
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