A model for in situ plan of care for a critically unstable pediatric patient following I-131 MIBG infusion
© 2020 Wiley Periodicals LLC..
Recent clinical trials have moved iodine-131 (I-131) metaiodobenzylguanidine (MIBG) therapy into frontline management of high-risk neuroblastoma. With this expansion, it is reasonable to anticipate the need for intensive care level resuscitations. Radiation exposure remains the greatest risk to health care professionals managing these patients. We combined shock simulation scenario data with actual radiation dosimetry data to create a care model allowing for aggressive, prolonged in situ resuscitation of a critically ill pediatric patient after I-131 MIBG administration. This model will maintain a critical care provider's radiation level below 10% of the annual occupational dose limit (5 mSv, 500 mrem) per patient managed.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:67 |
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| Enthalten in: |
Pediatric blood & cancer - 67(2020), 11 vom: 01. Nov., Seite e28665 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Flori, Heidi Rosanna [VerfasserIn] |
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| Links: |
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| Themen: |
3-Iodobenzylguanidine |
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| Anmerkungen: |
Date Completed 19.01.2021 Date Revised 19.01.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1002/pbc.28665 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM314009833 |
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| 520 | |a Recent clinical trials have moved iodine-131 (I-131) metaiodobenzylguanidine (MIBG) therapy into frontline management of high-risk neuroblastoma. With this expansion, it is reasonable to anticipate the need for intensive care level resuscitations. Radiation exposure remains the greatest risk to health care professionals managing these patients. We combined shock simulation scenario data with actual radiation dosimetry data to create a care model allowing for aggressive, prolonged in situ resuscitation of a critically ill pediatric patient after I-131 MIBG administration. This model will maintain a critical care provider's radiation level below 10% of the annual occupational dose limit (5 mSv, 500 mrem) per patient managed | ||
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| 700 | 1 | |a Yanik, Gregory Anthony |e verfasserin |4 aut | |
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