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Platelet Dysfunction Diseases and Conditions : Clinical Implications and Considerations

INTRODUCTION: Platelet diseases and dysfunction are taught early in medical school to all future physicians. Understanding of the coagulation cascade and hemostatic mechanisms has allowed for targeted pharmacological therapies that have been significantly impactful in clinical practice. Platelets are an early participant in hemostasis physiologically and under pathophysiological states

METHODS: A review of literature involving platelet disfunction

RESULTS: Various presentations of platelet diseases and dysfunction challenge clinicians and require a firm understanding of normal platelet function, drugs that mediate or modulate platelet effectiveness, and nonpharmacologic etiologies of platelet diseases and dysfunction with corresponding best practice treatment approaches

CONCLUSION: This review summarizes normal and abnormal states associated with platelets and treatment strategies

Year of Publication: 2020
Contained in: Advances in therapy Vol. 37, No. 9 (2020), p. 3707-3722
All journal articles: Search for all articles in this journal
Language: English
Contributors: Kaye, Alan D | Author
Jeha, George M
Moll, Vanessa
Ward, Ceressa T
Watson, Matthew R
Wynn, John Thomas
Hockstein, Maxwell A
Hall, Kevin M
Viswanath, Omar
Urits, Ivan
Prabhakar, Amit
Cornett, Elyse M
Full text access:
Electronic availability is being checked...
Links: Full Text (dx.doi.org)
Keywords: Hemostasis
Journal Article
Platelet disfunction
Review
Systemic lupus erythematosus
Thrombotic thrombocytopenic purpura
ISSN: 1865-8652
Note: Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Notes: Date Revised 08.10.2020
published: Print-Electronic
Citation Status In-Process
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
PMID:
    32729008
Physical Description: Online-Ressource
ID (e.g. DOI, URN): 10.1007/s12325-020-01453-4
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520 |a METHODS: A review of literature involving platelet disfunction 
520 |a RESULTS: Various presentations of platelet diseases and dysfunction challenge clinicians and require a firm understanding of normal platelet function, drugs that mediate or modulate platelet effectiveness, and nonpharmacologic etiologies of platelet diseases and dysfunction with corresponding best practice treatment approaches 
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