Pleural translocation and lesions by pulmonary exposed multi-walled carbon nanotubes
©2020 The Japanese Society of Toxicologic Pathology..
Carbon nanotubes (CNTs) are recently developed tubular nanomaterials, with diameters ranging from a few nanometers to tens of nanometers, and the length reaching up to several micrometers. They can be either single-walled carbon nanotubes (SWCNTs) or multi-walled carbon nanotubes (MWCNTs). Due to their nano-scaled structure, CNTs have a unique set of mechanical, electrical, and chemical properties that make them useful in information technologies, optoelectronics, energy technologies, material sciences, medical technologies, and other fields. However, with the wide application and increasing production of CNTs, their potential risks have led to concerns regarding their impact on environment and health. The shape of some types of CNTs is similar to asbestos fibers, which suggests that these CNTs may cause characteristic pleural diseases similar to those found in asbestos-exposed humans, such as pleural plaques and malignant mesothelioma. Experimental data indicate that CNTs can induce lung and pleural lesions, inflammation, pleural fibrosis, lung tumors, and malignant mesothelioma upon inhalation in the experimental animals. In this review, we focus on the potential of MWCNTs to induce diseases similar to those by asbestos, molecular and cellular mechanisms associated with these diseases, and we discuss a method for evaluating the pleural toxicity of MWCNTs.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2020 |
---|---|
Erschienen: |
2020 |
Enthalten in: |
Zur Gesamtaufnahme - volume:33 |
---|---|
Enthalten in: |
Journal of toxicologic pathology - 33(2020), 3 vom: 14. Juli, Seite 145-151 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Wang, Qiong [VerfasserIn] |
---|
Links: |
---|
Themen: |
Asbestos |
---|
Anmerkungen: |
Date Revised 28.09.2020 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
---|
doi: |
10.1293/tox.2019-0075 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM313398801 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM313398801 | ||
003 | DE-627 | ||
005 | 20231225150505.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231225s2020 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1293/tox.2019-0075 |2 doi | |
028 | 5 | 2 | |a pubmed24n1044.xml |
035 | |a (DE-627)NLM313398801 | ||
035 | |a (NLM)32764839 | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Wang, Qiong |e verfasserin |4 aut | |
245 | 1 | 0 | |a Pleural translocation and lesions by pulmonary exposed multi-walled carbon nanotubes |
264 | 1 | |c 2020 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Revised 28.09.2020 | ||
500 | |a published: Print-Electronic | ||
500 | |a Citation Status PubMed-not-MEDLINE | ||
520 | |a ©2020 The Japanese Society of Toxicologic Pathology. | ||
520 | |a Carbon nanotubes (CNTs) are recently developed tubular nanomaterials, with diameters ranging from a few nanometers to tens of nanometers, and the length reaching up to several micrometers. They can be either single-walled carbon nanotubes (SWCNTs) or multi-walled carbon nanotubes (MWCNTs). Due to their nano-scaled structure, CNTs have a unique set of mechanical, electrical, and chemical properties that make them useful in information technologies, optoelectronics, energy technologies, material sciences, medical technologies, and other fields. However, with the wide application and increasing production of CNTs, their potential risks have led to concerns regarding their impact on environment and health. The shape of some types of CNTs is similar to asbestos fibers, which suggests that these CNTs may cause characteristic pleural diseases similar to those found in asbestos-exposed humans, such as pleural plaques and malignant mesothelioma. Experimental data indicate that CNTs can induce lung and pleural lesions, inflammation, pleural fibrosis, lung tumors, and malignant mesothelioma upon inhalation in the experimental animals. In this review, we focus on the potential of MWCNTs to induce diseases similar to those by asbestos, molecular and cellular mechanisms associated with these diseases, and we discuss a method for evaluating the pleural toxicity of MWCNTs | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Review | |
650 | 4 | |a asbestos | |
650 | 4 | |a multi-walled carbon nanotubes | |
650 | 4 | |a pleural lesions | |
650 | 4 | |a pleural translocation | |
700 | 1 | |a Wang, Qiqi |e verfasserin |4 aut | |
700 | 1 | |a Zhao, Ziyue |e verfasserin |4 aut | |
700 | 1 | |a Alexander, David B |e verfasserin |4 aut | |
700 | 1 | |a Zhao, Dahai |e verfasserin |4 aut | |
700 | 1 | |a Xu, Jiegou |e verfasserin |4 aut | |
700 | 1 | |a Tsuda, Hiroyuki |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Journal of toxicologic pathology |d 1997 |g 33(2020), 3 vom: 14. Juli, Seite 145-151 |w (DE-627)NLM092587402 |x 0914-9198 |7 nnns |
773 | 1 | 8 | |g volume:33 |g year:2020 |g number:3 |g day:14 |g month:07 |g pages:145-151 |
856 | 4 | 0 | |u http://dx.doi.org/10.1293/tox.2019-0075 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 33 |j 2020 |e 3 |b 14 |c 07 |h 145-151 |