Modelling the Effectiveness of Epidemic Control Measures in Preventing the Transmission of COVID-19 in Malaysia
Malaysia is currently facing an outbreak of COVID-19. We aim to present the first study in Malaysia to report the reproduction numbers and develop a mathematical model forecasting COVID-19 transmission by including isolation, quarantine, and movement control measures. We utilized a susceptible, exposed, infectious, and recovered (SEIR) model by incorporating isolation, quarantine, and movement control order (MCO) taken in Malaysia. The simulations were fitted into the Malaysian COVID-19 active case numbers, allowing approximation of parameters consisting of probability of transmission per contact (β), average number of contacts per day per case (ζ), and proportion of close-contact traced per day (q). The effective reproduction number (Rt) was also determined through this model. Our model calibration estimated that (β), (ζ), and (q) were 0.052, 25 persons, and 0.23, respectively. The (Rt) was estimated to be 1.68. MCO measures reduce the peak number of active COVID-19 cases by 99.1% and reduce (ζ) from 25 (pre-MCO) to 7 (during MCO). The flattening of the epidemic curve was also observed with the implementation of these control measures. We conclude that isolation, quarantine, and MCO measures are essential to break the transmission of COVID-19 in Malaysia.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2020 |
|---|---|
| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:17 |
|---|---|
| Enthalten in: |
International journal of environmental research and public health - 17(2020), 15 vom: 30. Juli |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Gill, Balvinder Singh [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
And recovered (SEIR) |
|---|
| Anmerkungen: |
Date Completed 21.08.2020 Date Revised 03.11.2023 published: Electronic Citation Status MEDLINE |
|---|
| doi: |
10.3390/ijerph17155509 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM313269106 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM313269106 | ||
| 003 | DE-627 | ||
| 005 | 20231225150220.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3390/ijerph17155509 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1044.xml |
| 035 | |a (DE-627)NLM313269106 | ||
| 035 | |a (NLM)32751669 | ||
| 035 | |a (PII)E5509 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Gill, Balvinder Singh |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Modelling the Effectiveness of Epidemic Control Measures in Preventing the Transmission of COVID-19 in Malaysia |
| 264 | 1 | |c 2020 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 21.08.2020 | ||
| 500 | |a Date Revised 03.11.2023 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Malaysia is currently facing an outbreak of COVID-19. We aim to present the first study in Malaysia to report the reproduction numbers and develop a mathematical model forecasting COVID-19 transmission by including isolation, quarantine, and movement control measures. We utilized a susceptible, exposed, infectious, and recovered (SEIR) model by incorporating isolation, quarantine, and movement control order (MCO) taken in Malaysia. The simulations were fitted into the Malaysian COVID-19 active case numbers, allowing approximation of parameters consisting of probability of transmission per contact (β), average number of contacts per day per case (ζ), and proportion of close-contact traced per day (q). The effective reproduction number (Rt) was also determined through this model. Our model calibration estimated that (β), (ζ), and (q) were 0.052, 25 persons, and 0.23, respectively. The (Rt) was estimated to be 1.68. MCO measures reduce the peak number of active COVID-19 cases by 99.1% and reduce (ζ) from 25 (pre-MCO) to 7 (during MCO). The flattening of the epidemic curve was also observed with the implementation of these control measures. We conclude that isolation, quarantine, and MCO measures are essential to break the transmission of COVID-19 in Malaysia | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a COVID-19 | |
| 650 | 4 | |a and recovered (SEIR) | |
| 650 | 4 | |a exposed | |
| 650 | 4 | |a infectious | |
| 650 | 4 | |a isolation | |
| 650 | 4 | |a mathematical modeling | |
| 650 | 4 | |a movement | |
| 650 | 4 | |a susceptible | |
| 700 | 1 | |a Jayaraj, Vivek Jason |e verfasserin |4 aut | |
| 700 | 1 | |a Singh, Sarbhan |e verfasserin |4 aut | |
| 700 | 1 | |a Mohd Ghazali, Sumarni |e verfasserin |4 aut | |
| 700 | 1 | |a Cheong, Yoon Ling |e verfasserin |4 aut | |
| 700 | 1 | |a Md Iderus, Nuur Hafizah |e verfasserin |4 aut | |
| 700 | 1 | |a Sundram, Bala Murali |e verfasserin |4 aut | |
| 700 | 1 | |a Aris, Tahir Bin |e verfasserin |4 aut | |
| 700 | 1 | |a Mohd Ibrahim, Hishamshah |e verfasserin |4 aut | |
| 700 | 1 | |a Hong, Boon Hao |e verfasserin |4 aut | |
| 700 | 1 | |a Labadin, Jane |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t International journal of environmental research and public health |d 2004 |g 17(2020), 15 vom: 30. Juli |w (DE-627)NLM162777434 |x 1660-4601 |7 nnns |
| 773 | 1 | 8 | |g volume:17 |g year:2020 |g number:15 |g day:30 |g month:07 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.3390/ijerph17155509 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 17 |j 2020 |e 15 |b 30 |c 07 | ||