Metabolic communication during exercise
The coordination of nutrient sensing, delivery, uptake and utilization is essential for maintaining cellular, tissue and whole-body homeostasis. Such synchronization can be achieved only if metabolic information is communicated between the cells and tissues of the entire organism. During intense exercise, the metabolic demand of the body can increase approximately 100-fold. Thus, exercise is a physiological state in which intertissue communication is of paramount importance. In this Review, we discuss the physiological processes governing intertissue communication during exercise and the molecules mediating such cross-talk.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2020 |
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Erschienen: |
2020 |
Enthalten in: |
Zur Gesamtaufnahme - volume:2 |
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Enthalten in: |
Nature metabolism - 2(2020), 9 vom: 03. Sept., Seite 805-816 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Murphy, Robyn M [VerfasserIn] |
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Anmerkungen: |
Date Completed 04.01.2021 Date Revised 18.02.2021 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1038/s42255-020-0258-x |
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funding: |
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PPN (Katalog-ID): |
NLM313230897 |
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520 | |a The coordination of nutrient sensing, delivery, uptake and utilization is essential for maintaining cellular, tissue and whole-body homeostasis. Such synchronization can be achieved only if metabolic information is communicated between the cells and tissues of the entire organism. During intense exercise, the metabolic demand of the body can increase approximately 100-fold. Thus, exercise is a physiological state in which intertissue communication is of paramount importance. In this Review, we discuss the physiological processes governing intertissue communication during exercise and the molecules mediating such cross-talk | ||
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