Use of hyperbaric oxygen therapy of purpura fulminans in an extremely low birth weight preterm : A case report

Purpura fulminans (PF) is a rare and fatal complication of septic shock or diffuse intravascular coagulation (DIC) resulting in skin and soft tissue necrosis. PF can be caused by congenital or acquired protein C (PC) or protein S (PS) deficiency. The most common cause of PF in a neonate is sepsis. In our extremely low birth weight preterm case, due to PF that started in the right-hand fingers, examination was made and protein S deficiency was detected as well as MTHFR (A1298C) and Factor V Leiden (R506Q) homozygous mutations. While being unresponsive to fresh frozen plasma (FFP) and unfractionated heparin (UFH) therapy, we want to highlight the curative treatment with hyperbaric oxygen (HBOT), which has not previously been used in extremely low birth weight preterm infants for this purpose.

Medienart:

E-Artikel

Erscheinungsjahr:

2023

Erschienen:

2023

Enthalten in:

Zur Gesamtaufnahme - volume:16

Enthalten in:

Journal of neonatal-perinatal medicine - 16(2023), 2 vom: 31., Seite 339-342

Sprache:

Englisch

Beteiligte Personen:

Yılmaz, A [VerfasserIn]
Kaya, N [VerfasserIn]
Meriç, R [VerfasserIn]
Bayramli, Z [VerfasserIn]
Öroğlu, B [VerfasserIn]
Celkan, T T [VerfasserIn]
Vural, M [VerfasserIn]
Perk, Y [VerfasserIn]

Links:

Volltext

Themen:

9005-49-6
Case Reports
Heparin
Hyperbaric oxygen therapy
Journal Article
Preterm
Purpura fulminans

Anmerkungen:

Date Completed 03.07.2023

Date Revised 03.07.2023

published: Print

Citation Status MEDLINE

doi:

10.3233/NPM-200428

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM313171440