Pituitary hyperplasia mimicking thyrotropin-producing pituitary adenoma in the patient with resistance to thyroid hormone : a case report

The syndrome of inappropriate thyroid-stimulating hormone (TSH) secretion is characterized by high circulating thyroid hormone concentrations in the presence of non-suppressed TSH. After exclusion of the laboratory interference, TSH-secreting pituitary adenoma (TSHoma) or resistance to thyroid hormone-beta (RTH-β) should be suspected. The presence of a pituitary adenoma on the hypothalamic-pituitary imaging supports the diagnosis of TSHoma. However, the incidental findings of non-functioning pituitary adenomas may appear in patients with RTH-β. Abnormal MRI finding in the RTH-β patient also includes pituitary enlargement from thyrotroph hyperplasia. We herein reported a patient with inappropriate TSH secretion who has pituitary hyperplasia mimicking TSHoma. This case illustrates the diagnostic tests to distinguish an RTH-β from TSHoma.

Medienart:

E-Artikel

Erscheinungsjahr:

2022

Erschienen:

2022

Enthalten in:

Zur Gesamtaufnahme - volume:132

Enthalten in:

The International journal of neuroscience - 132(2022), 2 vom: 01. Feb., Seite 207-211

Sprache:

Englisch

Beteiligte Personen:

Suntornlohanakul, Onnicha [VerfasserIn]
Sriphrapradang, Chutintorn [VerfasserIn]

Links:

Volltext

Themen:

9002-71-5
Case Reports
Hyperthyroxinemia
Journal Article
Magnetic resonance imaging
Pituitary neoplasm
Thyroid Hormones
Thyroid function tests
Thyroid hormone resistance syndrome
Thyrotropin

Anmerkungen:

Date Completed 13.04.2022

Date Revised 13.04.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1080/00207454.2020.1803304

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM313028648