On the mechanism of ophiobolin F synthase and the absolute configuration of its product by isotopic labelling experiments
An ophiobolin F synthase homolog was discovered from Aspergillus calidoustus CBS121601. The cyclisation mechanism of this terpene synthase was investigated by extensive isotopic labelling experiments and the absolute configuration of its product ophiobolin F was elucidated by enantioselective deuteration.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2020 |
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Erschienen: |
2020 |
Enthalten in: |
Zur Gesamtaufnahme - volume:18 |
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Enthalten in: |
Organic & biomolecular chemistry - 18(2020), 31 vom: 21. Aug., Seite 6072-6076 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Quan, Zhiyang [VerfasserIn] |
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Links: |
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Themen: |
Alkyl and Aryl Transferases |
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Anmerkungen: |
Date Completed 14.03.2022 Date Revised 14.03.2022 published: Print-Electronic Citation Status MEDLINE |
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doi: |
10.1039/d0ob01470b |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM313007012 |
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520 | |a An ophiobolin F synthase homolog was discovered from Aspergillus calidoustus CBS121601. The cyclisation mechanism of this terpene synthase was investigated by extensive isotopic labelling experiments and the absolute configuration of its product ophiobolin F was elucidated by enantioselective deuteration | ||
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