Kangaroo mother care alters chromogranin A and perfusion index in preterm babies
© 2020 Japan Pediatric Society..
BACKGROUND: While providing various benefits, concerns about the potential risks of kangaroo mother care, or skin-to-skin contact (SSC), between mother and her preterm infant hinder its widespread implementation in some resource- rich countries. In neonates, salivary chromogranin A (s-CgA) is elevated upon exposure to stress, whereas the perfusion index (PI) is associated with hemodynamics and peripheral perfusion. Here, we investigated the effects of SSC on s-CgA and the PI in preterm infants.
METHODS: Twelve infants were enrolled in the study. Factors associated with baseline s-CgA were analyzed. Baseline s-CgA and the level after SSC were compared. Secreted IgA in the saliva was compared as the control. The PI before, throughout, and after SSC were compared.
RESULTS: Baseline s-CgA was significantly lower in infants who were supplemented with baby formula milk in addition to breast milk before SSC (n = 2) compared with those fed with their mother's breast milk alone (n = 10, P = 0.03). SSC significantly decreased s-CgA in babies who were fed breast milk only before SSC (n = 10, P = 0.01) but not in those supplemented with formula milk before SSC (n = 2). Secreted IgA in saliva was not affected by SSC. The PI was significantly elevated during SSC (P = .01).
CONCLUSION: Our data indicate that SSC can reduce s-CgA levels when combined with mother's breast milk and increase the PI in preterm infants, thereby providing additional evidence of the benefit of SSC.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2021 |
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| Erschienen: |
2021 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:63 |
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| Enthalten in: |
Pediatrics international : official journal of the Japan Pediatric Society - 63(2021), 1 vom: 17. Jan., Seite 53-59 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Endo, Tomohiro [VerfasserIn] |
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| Links: |
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| Themen: |
Chromogranin A |
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| Anmerkungen: |
Date Completed 11.08.2021 Date Revised 11.08.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1111/ped.14350 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM311218113 |
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| 245 | 1 | 0 | |a Kangaroo mother care alters chromogranin A and perfusion index in preterm babies |
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| 500 | |a Date Completed 11.08.2021 | ||
| 500 | |a Date Revised 11.08.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2020 Japan Pediatric Society. | ||
| 520 | |a BACKGROUND: While providing various benefits, concerns about the potential risks of kangaroo mother care, or skin-to-skin contact (SSC), between mother and her preterm infant hinder its widespread implementation in some resource- rich countries. In neonates, salivary chromogranin A (s-CgA) is elevated upon exposure to stress, whereas the perfusion index (PI) is associated with hemodynamics and peripheral perfusion. Here, we investigated the effects of SSC on s-CgA and the PI in preterm infants | ||
| 520 | |a METHODS: Twelve infants were enrolled in the study. Factors associated with baseline s-CgA were analyzed. Baseline s-CgA and the level after SSC were compared. Secreted IgA in the saliva was compared as the control. The PI before, throughout, and after SSC were compared | ||
| 520 | |a RESULTS: Baseline s-CgA was significantly lower in infants who were supplemented with baby formula milk in addition to breast milk before SSC (n = 2) compared with those fed with their mother's breast milk alone (n = 10, P = 0.03). SSC significantly decreased s-CgA in babies who were fed breast milk only before SSC (n = 10, P = 0.01) but not in those supplemented with formula milk before SSC (n = 2). Secreted IgA in saliva was not affected by SSC. The PI was significantly elevated during SSC (P = .01) | ||
| 520 | |a CONCLUSION: Our data indicate that SSC can reduce s-CgA levels when combined with mother's breast milk and increase the PI in preterm infants, thereby providing additional evidence of the benefit of SSC | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a kangaroo mother care | |
| 650 | 4 | |a perfusion index | |
| 650 | 4 | |a preterm infants | |
| 650 | 4 | |a salivary chromogranin A | |
| 650 | 4 | |a skin-to-skin contact | |
| 650 | 7 | |a Chromogranin A |2 NLM | |
| 700 | 1 | |a Sampei, Mari |e verfasserin |4 aut | |
| 700 | 1 | |a Fukuda, Seiji |e verfasserin |4 aut | |
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