Hypercoagulation from Concomitant Administration of Tamoxifen and Warfarin
Copyright © 2020, Panahi et al..
Tamoxifen causing an increase in the anticoagulation effect of warfarin is suggested to be clinically significant, but cases so far have been largely undocumented. Current recommendations advise clinicians to proceed with caution during concomitant therapy. In the presence of other medications known to interact with warfarin, such as antibiotics, proton pump inhibitors, amiodarone, and azole antifungals, international normalized ratio (INR) elevations can possibly be exacerbated even further. We hereby present a case report and a review of significant literature on the use of tamoxifen and warfarin concurrently.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2020 |
|---|---|
| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
|---|---|
| Enthalten in: |
Cureus - 12(2020), 5 vom: 14. Mai, Seite e8114 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Panahi, Ladan [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Breast cancer |
|---|
| Anmerkungen: |
Date Revised 28.09.2020 published: Electronic Citation Status PubMed-not-MEDLINE |
|---|
| doi: |
10.7759/cureus.8114 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM311211801 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM311211801 | ||
| 003 | DE-627 | ||
| 005 | 20231225141754.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.7759/cureus.8114 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1037.xml |
| 035 | |a (DE-627)NLM311211801 | ||
| 035 | |a (NLM)32542167 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Panahi, Ladan |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Hypercoagulation from Concomitant Administration of Tamoxifen and Warfarin |
| 264 | 1 | |c 2020 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Revised 28.09.2020 | ||
| 500 | |a published: Electronic | ||
| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a Copyright © 2020, Panahi et al. | ||
| 520 | |a Tamoxifen causing an increase in the anticoagulation effect of warfarin is suggested to be clinically significant, but cases so far have been largely undocumented. Current recommendations advise clinicians to proceed with caution during concomitant therapy. In the presence of other medications known to interact with warfarin, such as antibiotics, proton pump inhibitors, amiodarone, and azole antifungals, international normalized ratio (INR) elevations can possibly be exacerbated even further. We hereby present a case report and a review of significant literature on the use of tamoxifen and warfarin concurrently | ||
| 650 | 4 | |a Case Reports | |
| 650 | 4 | |a breast cancer | |
| 650 | 4 | |a cancer anticoagulation | |
| 650 | 4 | |a dvt prophylaxis | |
| 650 | 4 | |a inr | |
| 650 | 4 | |a prothrombin | |
| 650 | 4 | |a tamoxifen | |
| 650 | 4 | |a warfarin | |
| 700 | 1 | |a Saenz Ii, Javier A |e verfasserin |4 aut | |
| 700 | 1 | |a Nguyen, Nam |e verfasserin |4 aut | |
| 700 | 1 | |a Udeani, George |e verfasserin |4 aut | |
| 700 | 1 | |a Surani, Salim |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Cureus |d 2013 |g 12(2020), 5 vom: 14. Mai, Seite e8114 |w (DE-627)NLM24118083X |x 2168-8184 |7 nnns |
| 773 | 1 | 8 | |g volume:12 |g year:2020 |g number:5 |g day:14 |g month:05 |g pages:e8114 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.7759/cureus.8114 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 12 |j 2020 |e 5 |b 14 |c 05 |h e8114 | ||