Prevalence of mucoepidermoid carcinoma among intraoral minor salivary gland tumors : A systematic review and meta-analysis

© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd..

This study aimed to synthetize and critically appraise available evidence regarding mucoepidermoid carcinoma (MEC) prevalence among intraoral minor salivary gland tumors (MiSGT). Five main electronic databases and three grey literature databases were searched. The risk of bias (RoB) was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Studies Reporting Prevalence Data. Proportion meta-analyses were performed. From 1321 studies identified, 82 were included in qualitative synthesis and 80 in meta-analyses. Sixteen were classified as high, 33 as moderate, and 33 as low RoB. A total of 12 774 MiSGT were found, of which overall MEC prevalence was 16.5% (95% Confidence Interval [95% CI] = 14.8%-18.4%). Most MiSGT were found in the palate (n = 7115), although MEC pooled prevalence in this anatomic location was only 13.6% (95% CI = 11.7%-15.6%). The retromolar area presented the highest pooled prevalence (58.9%; 95% CI = 47.0%-70.3%), followed by gingiva (28.8%; 95% CI = 22.7%-35.4%) and tongue (27.2%; 95% CI = 21.2%-33.6%). Regarding geographic location, Middle East presented the highest pooled prevalence (20.8%; 95% CI = 14.8%-27.6%), followed by America (20.0%, 95% CI = 17.2%-23%) and Europe (15.6%; 95% CI = 9.2%-23.5%). Among MiSGT, the MEC overall prevalence was approximately 16.5%. Although most MiSGT were found in the palate, the retromolar area was proportionally more affected by MEC.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:49

Enthalten in:

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 49(2020), 8 vom: Sept., Seite 720-726

Sprache:

Englisch

Beteiligte Personen:

Poletto, André Goulart [VerfasserIn]
Mello, Fernanda Weber [VerfasserIn]
Melo, Gilberto [VerfasserIn]
Rivero, Elena Riet Correa [VerfasserIn]

Links:

Volltext

Themen:

Journal Article
Meta-Analysis
Meta-analysis
Mucoepidermoid carcinoma
Prevalence
Salivary gland neoplasms
Systematic Review
Systematic review

Anmerkungen:

Date Completed 21.12.2020

Date Revised 31.05.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1111/jop.13073

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM311109780