Diagnostic Tools for Coronavirus Disease (COVID-19) : Comparing CT and RT-PCR Viral Nucleic Acid Testing

OBJECTIVE. Multiple studies suggest CT should be a primary diagnostic tool for coronavirus disease (COVID-19) because they reported sensitivities with CT far superior to that of reverse transcriptase polymerase chain reaction (RT-PCR) testing. This review aimed to assess these reports and found chest CT to have a clinical utility that is limited, particularly for patients who show no symptoms and patients who are screened early in disease progression. CONCLUSION. CT has limited sensitivity for COVID-19 and a lower specificity than RT-PCR testing, and it carries a risk of exposing providers to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Chest CT should be considered a supplemental diagnostic tool, particularly for patients who show symptoms.

Media Type:

Electronic Article

Year of Publication:

2020

Contained In:

AJR. American journal of roentgenology - Vol. 215, No. 4 (2020), p. 834-838

Language:

English

Contributors:

Waller, Joseph V
Kaur, Parveer
Tucker, Amy
Lin, Keldon K
Diaz, Michael J
Henry, Travis S
Hope, Michael

Links:

Volltext

Keywords:

*Reverse Transcriptase Polymerase Chain Reaction
*Tomography, X-Ray Computed
Betacoronavirus
COVID-19
Chest CT
Clinical Laboratory Techniques
Coronavirus Infections
Coronavirus disease
Humans
Journal Article
Pandemics
Pneumonia, Viral
RT-PCR
Review
SARS-CoV-2
Sensitivity
Sensitivity and Specificity
Severe acute respiratory syndrome coronavirus 2
Specificity

Notes:

Date Completed 01.10.2020

Date Revised 01.10.2020

published: Print-Electronic

Citation Status MEDLINE

Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Physical Description:

Online-Ressource

doi:

10.2214/AJR.20.23418

PMID:

32412790

PPN (Catalogue-ID):

NLM310824192