Association between low-fat enteral nutrition after esophagectomy and a lower incidence of chyle leakage : A call for more and better evidence

OBJECTIVE: Reliable methods to prevent chyle leakage after esophagectomy are needed. This retrospective study was performed to evaluate the correlation between low-fat nutrition and the incidence of chyle leakage after esophagectomy.

METHODS: This multicenter retrospective case-control study involved patients who underwent Ivor Lewis esophagectomy from December 2012 to August 2017. Tube feeding was started on postoperative day 1 with a normal fat-containing formula (control group, 203 patients) or low fat-containing formula (241 patients).

RESULTS: The patients in the control group and low-fat group had a similar incidence of chyle leakage (7 [3.4%] vs. 19 [9.4%], respectively) and anastomotic leakage (4 [2.0%] vs. 11 [5.4%], respectively). The multivariate logistic regression indicated that high-volume surgeon experience (performance of ≥100 esophagectomies per year) was correlated with a lower incidence of chyle leakage (odds ratio, 0.280; 95% confidence interval, 0.110-0.712), whereas low-fat nutrition was correlated with an increased risk of anastomotic leakage (odds ratio, 5.995; 95% confidence interval, 1.201-29.925).

CONCLUSION: Prophylactic low-fat enteral nutrition following esophagectomy might not decrease the risk of chyle leakage. More and better evidence is needed.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:48

Enthalten in:

The Journal of international medical research - 48(2020), 5 vom: 14. Mai, Seite 300060520926370

Sprache:

Englisch

Beteiligte Personen:

Zhang, Chu [VerfasserIn]
Gong, Longbo [VerfasserIn]
Wu, Wenbin [VerfasserIn]
Zhang, Miao [VerfasserIn]
Zhang, Hui [VerfasserIn]
Zhao, Chen [VerfasserIn]

Links:

Volltext

Themen:

Anastomotic leakage
Chyle leakage
Esophageal cancer
Esophagectomy
Ivor Lewis
Journal Article
Low-fat formula
Multicenter Study
Serratus anterior plane block

Anmerkungen:

Date Completed 08.03.2021

Date Revised 08.03.2021

published: Print

Citation Status MEDLINE

doi:

10.1177/0300060520926370

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM310494095