Association between low-fat enteral nutrition after esophagectomy and a lower incidence of chyle leakage : A call for more and better evidence
OBJECTIVE: Reliable methods to prevent chyle leakage after esophagectomy are needed. This retrospective study was performed to evaluate the correlation between low-fat nutrition and the incidence of chyle leakage after esophagectomy.
METHODS: This multicenter retrospective case-control study involved patients who underwent Ivor Lewis esophagectomy from December 2012 to August 2017. Tube feeding was started on postoperative day 1 with a normal fat-containing formula (control group, 203 patients) or low fat-containing formula (241 patients).
RESULTS: The patients in the control group and low-fat group had a similar incidence of chyle leakage (7 [3.4%] vs. 19 [9.4%], respectively) and anastomotic leakage (4 [2.0%] vs. 11 [5.4%], respectively). The multivariate logistic regression indicated that high-volume surgeon experience (performance of ≥100 esophagectomies per year) was correlated with a lower incidence of chyle leakage (odds ratio, 0.280; 95% confidence interval, 0.110-0.712), whereas low-fat nutrition was correlated with an increased risk of anastomotic leakage (odds ratio, 5.995; 95% confidence interval, 1.201-29.925).
CONCLUSION: Prophylactic low-fat enteral nutrition following esophagectomy might not decrease the risk of chyle leakage. More and better evidence is needed.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2020 |
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Erschienen: |
2020 |
Enthalten in: |
Zur Gesamtaufnahme - volume:48 |
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Enthalten in: |
The Journal of international medical research - 48(2020), 5 vom: 14. Mai, Seite 300060520926370 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Zhang, Chu [VerfasserIn] |
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Links: |
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Themen: |
Anastomotic leakage |
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Anmerkungen: |
Date Completed 08.03.2021 Date Revised 08.03.2021 published: Print Citation Status MEDLINE |
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doi: |
10.1177/0300060520926370 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM310494095 |
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500 | |a Citation Status MEDLINE | ||
520 | |a OBJECTIVE: Reliable methods to prevent chyle leakage after esophagectomy are needed. This retrospective study was performed to evaluate the correlation between low-fat nutrition and the incidence of chyle leakage after esophagectomy | ||
520 | |a METHODS: This multicenter retrospective case-control study involved patients who underwent Ivor Lewis esophagectomy from December 2012 to August 2017. Tube feeding was started on postoperative day 1 with a normal fat-containing formula (control group, 203 patients) or low fat-containing formula (241 patients) | ||
520 | |a RESULTS: The patients in the control group and low-fat group had a similar incidence of chyle leakage (7 [3.4%] vs. 19 [9.4%], respectively) and anastomotic leakage (4 [2.0%] vs. 11 [5.4%], respectively). The multivariate logistic regression indicated that high-volume surgeon experience (performance of ≥100 esophagectomies per year) was correlated with a lower incidence of chyle leakage (odds ratio, 0.280; 95% confidence interval, 0.110-0.712), whereas low-fat nutrition was correlated with an increased risk of anastomotic leakage (odds ratio, 5.995; 95% confidence interval, 1.201-29.925) | ||
520 | |a CONCLUSION: Prophylactic low-fat enteral nutrition following esophagectomy might not decrease the risk of chyle leakage. More and better evidence is needed | ||
650 | 4 | |a Journal Article | |
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650 | 4 | |a Chyle leakage | |
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650 | 4 | |a esophageal cancer | |
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700 | 1 | |a Zhang, Miao |e verfasserin |4 aut | |
700 | 1 | |a Zhang, Hui |e verfasserin |4 aut | |
700 | 1 | |a Zhao, Chen |e verfasserin |4 aut | |
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