Biliary reconstruction and complications in living donor liver transplantation
Copyright © 2020 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved..
For a technically successful liver transplant (LT), secure bile duct anastomosis to prevent biliary complications (BC's) like biliary anastomotic stricture (BAS) and bile leak (BL) is mandatory. BC's after living donor liver transplantation (LDLT) are relatively more common compared to deceased donor LT (DDLT), particularly owing to surgical factors (small diameter, and/or multiple bile duct openings on the graft), and non-surgical factors (immunologic reactions). Adequate blood supply to the bile duct both in donor and recipient, meticulous anastomotic technique, mucosal eversion for better approximation thus avoiding lesser fibrosis, proper use of internal or external stent drainage, and tension-free anastomosis, may contribute to the decrease of BC's after LDLT. Further, if BC's are not dealt with in a timely manner, these could progressively lead to severe morbidities and even mortality. While the endoscopic approach is preferred initially to deal with biliary leaks or strictures, the more invasive percutaneous approach may be required in case of endoscopic failure. Dedicated and experienced endoscopists, and interventional radiologists are key members of the multidisciplinary team in a successful LDLT program. In this review, we have tried to summarize current concepts in surgical techniques of biliary reconstruction in LDLT, incidence and risk factors for BC's, and principles followed to try and reduce the incidence of the same.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2020 |
|---|---|
| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:82S |
|---|---|
| Enthalten in: |
International journal of surgery (London, England) - 82S(2020) vom: 01. Okt., Seite 138-144 |
| Sprache: |
Englisch |
|---|
| Beteiligte Personen: |
Jung, Dong-Hwan [VerfasserIn] |
|---|
| Links: |
|---|
| Themen: |
Biliary complication |
|---|
| Anmerkungen: |
Date Completed 03.03.2021 Date Revised 07.12.2022 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.ijsu.2020.04.069 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM30970412X |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM30970412X | ||
| 003 | DE-627 | ||
| 005 | 20231225134512.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2020 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1016/j.ijsu.2020.04.069 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n1032.xml |
| 035 | |a (DE-627)NLM30970412X | ||
| 035 | |a (NLM)32387205 | ||
| 035 | |a (PII)S1743-9191(20)30369-1 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a eng | ||
| 100 | 1 | |a Jung, Dong-Hwan |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Biliary reconstruction and complications in living donor liver transplantation |
| 264 | 1 | |c 2020 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 03.03.2021 | ||
| 500 | |a Date Revised 07.12.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2020 IJS Publishing Group Ltd. Published by Elsevier Ltd. All rights reserved. | ||
| 520 | |a For a technically successful liver transplant (LT), secure bile duct anastomosis to prevent biliary complications (BC's) like biliary anastomotic stricture (BAS) and bile leak (BL) is mandatory. BC's after living donor liver transplantation (LDLT) are relatively more common compared to deceased donor LT (DDLT), particularly owing to surgical factors (small diameter, and/or multiple bile duct openings on the graft), and non-surgical factors (immunologic reactions). Adequate blood supply to the bile duct both in donor and recipient, meticulous anastomotic technique, mucosal eversion for better approximation thus avoiding lesser fibrosis, proper use of internal or external stent drainage, and tension-free anastomosis, may contribute to the decrease of BC's after LDLT. Further, if BC's are not dealt with in a timely manner, these could progressively lead to severe morbidities and even mortality. While the endoscopic approach is preferred initially to deal with biliary leaks or strictures, the more invasive percutaneous approach may be required in case of endoscopic failure. Dedicated and experienced endoscopists, and interventional radiologists are key members of the multidisciplinary team in a successful LDLT program. In this review, we have tried to summarize current concepts in surgical techniques of biliary reconstruction in LDLT, incidence and risk factors for BC's, and principles followed to try and reduce the incidence of the same | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Review | |
| 650 | 4 | |a Biliary complication | |
| 650 | 4 | |a Biliary reconstruction | |
| 650 | 4 | |a Living donor liver transplantation | |
| 700 | 1 | |a Ikegami, Toru |e verfasserin |4 aut | |
| 700 | 1 | |a Balci, Deniz |e verfasserin |4 aut | |
| 700 | 1 | |a Bhangui, Prashant |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t International journal of surgery (London, England) |d 2004 |g 82S(2020) vom: 01. Okt., Seite 138-144 |w (DE-627)NLM169227847 |x 1743-9159 |7 nnns |
| 773 | 1 | 8 | |g volume:82S |g year:2020 |g day:01 |g month:10 |g pages:138-144 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.ijsu.2020.04.069 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 82S |j 2020 |b 01 |c 10 |h 138-144 | ||