Synthetic studies towards anti-SARS agents : application of an indium-mediated allylation of α-aminoaldehydes as the key step towards an intermediate
Copyright © 2004 Elsevier Ltd. All rights reserved..
AG7088 was identified as a good starting point for modification, leading to an efficient and bio-available inhibitor for the SARS coronavirus main proteinase (SARS-CoV Mpro). Synthesis of intermediate 1 and analogues proceeded via a highly diastereoselective indium-mediated allylation of α-aminoaldehydes.
Medienart: |
E-Artikel |
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Erscheinungsjahr: |
2004 |
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Erschienen: |
2004 |
Enthalten in: |
Zur Gesamtaufnahme - volume:45 |
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Enthalten in: |
Tetrahedron letters - 45(2004), 52 vom: 20. Dez., Seite 9501-9504 |
Sprache: |
Englisch |
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Beteiligte Personen: |
Chng, Shu-Sin [VerfasserIn] |
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Links: |
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Themen: |
AG7088 |
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Anmerkungen: |
Date Revised 18.04.2020 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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doi: |
10.1016/j.tetlet.2004.10.146 |
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funding: |
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Förderinstitution / Projekttitel: |
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PPN (Katalog-ID): |
NLM308723635 |
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