Portable pulsed xenon ultraviolet light disinfection in a teaching hospital animal laboratory in China
Copyright © 2020 Elsevier B.V. All rights reserved..
An animal laboratory in a teaching hospital is a possible cause of cross infection. We aimed to assess the infection control in our animal laboratory and evaluate the disinfectant effects of a portable pulsed xenon ultraviolet (PX-UV) machine. Samples were taken from the surface of research tables, other high touch places, such as doorknobs, weighing scales, and handles of trolleys, and from air in the barrier system pre- and post-manual cleaning and post-PX-UV disinfection. The bacteria types were identified. We found that routine manual cleaning significantly reduced bacterial colony form unit (CFU)/cm2 (P = .02), and the median of CFU/cm2 reduced from 0.5 pre-cleaning to zero post-cleaning. PX-UV disinfection also significantly reduced residual bacterial counts (P = .002), with the highest counts 10 pre-PX-UV disinfection and 1 afterwards. Without manual cleaning, PX-UV disinfected surfaces significantly (P < .001), median count 6 pre-PX-UV disinfection and zero afterwards. PX-UV significantly reduced bacterial colony counts in the air with the median count falling from 6 to zero (P < .001). Some of the 21 species of pathogens we identified in the current study are pathogenic, resistant to antibiotics, and able to cause nosocomial infections and zoonosis. PX-UV reduced counts of most of the pathogens. PX-UV is an effective agent against these pathogens.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:207 |
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| Enthalten in: |
Journal of photochemistry and photobiology. B, Biology - 207(2020) vom: 08. Juni, Seite 111869 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Li, Jing-Jing [VerfasserIn] |
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| Links: |
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| Themen: |
3H3U766W84 |
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| Anmerkungen: |
Date Completed 12.01.2021 Date Revised 01.02.2021 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.jphotobiol.2020.111869 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM308633660 |
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| 520 | |a An animal laboratory in a teaching hospital is a possible cause of cross infection. We aimed to assess the infection control in our animal laboratory and evaluate the disinfectant effects of a portable pulsed xenon ultraviolet (PX-UV) machine. Samples were taken from the surface of research tables, other high touch places, such as doorknobs, weighing scales, and handles of trolleys, and from air in the barrier system pre- and post-manual cleaning and post-PX-UV disinfection. The bacteria types were identified. We found that routine manual cleaning significantly reduced bacterial colony form unit (CFU)/cm2 (P = .02), and the median of CFU/cm2 reduced from 0.5 pre-cleaning to zero post-cleaning. PX-UV disinfection also significantly reduced residual bacterial counts (P = .002), with the highest counts 10 pre-PX-UV disinfection and 1 afterwards. Without manual cleaning, PX-UV disinfected surfaces significantly (P < .001), median count 6 pre-PX-UV disinfection and zero afterwards. PX-UV significantly reduced bacterial colony counts in the air with the median count falling from 6 to zero (P < .001). Some of the 21 species of pathogens we identified in the current study are pathogenic, resistant to antibiotics, and able to cause nosocomial infections and zoonosis. PX-UV reduced counts of most of the pathogens. PX-UV is an effective agent against these pathogens | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Animal laboratory | |
| 650 | 4 | |a Disinfection | |
| 650 | 4 | |a Pulsed xenon ultraviolet light | |
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| 700 | 1 | |a Wang, Shan-Ni |e verfasserin |4 aut | |
| 700 | 1 | |a Qiao, Jiao-Jiao |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Li-Hua |e verfasserin |4 aut | |
| 700 | 1 | |a Li, Yu |e verfasserin |4 aut | |
| 700 | 1 | |a Wu, Yong |e verfasserin |4 aut | |
| 700 | 1 | |a Ding, Yan-Xia |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Mei-Mei |e verfasserin |4 aut | |
| 700 | 1 | |a Tian, Yun |e verfasserin |4 aut | |
| 700 | 1 | |a Liu, Yun-Bo |e verfasserin |4 aut | |
| 700 | 1 | |a Yan, Chen |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Chen |e verfasserin |4 aut | |
| 700 | 1 | |a Gao, Chang-Qing |e verfasserin |4 aut | |
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