Self-programmed nanovesicle to nanofiber transformation of a dipeptide appended bolaamphiphile and its dose dependent cytotoxic behaviour
Nanostructural transition of a small peptide bolaamphiphile via molecular self-assembly is a challenging task. Here, we report the self-programmed morphological transformation from nanovesicles to nanofibers of a smart peptide bolaamphiphile in its self-assembling hydrogel state. The nanostructural transition occurs based on the structural continuity of the β-sheet structures. Spectroscopic studies confirmed the different molecular arrangements of the two different nanostructures. Furthermore, the smart bolaamphiphile shows a dose-dependent cytotoxicity and cell-proliferation behaviour.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2014 |
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| Erschienen: |
2014 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:2 |
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| Enthalten in: |
Journal of materials chemistry. B - 2(2014), 32 vom: 28. Aug., Seite 5272-5279 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Maity, Indrajit [VerfasserIn] |
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| Links: |
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| Anmerkungen: |
Date Revised 08.04.2020 published: Print-Electronic Citation Status PubMed-not-MEDLINE |
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| doi: |
10.1039/c4tb00365a |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM308469496 |
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| 500 | |a Citation Status PubMed-not-MEDLINE | ||
| 520 | |a Nanostructural transition of a small peptide bolaamphiphile via molecular self-assembly is a challenging task. Here, we report the self-programmed morphological transformation from nanovesicles to nanofibers of a smart peptide bolaamphiphile in its self-assembling hydrogel state. The nanostructural transition occurs based on the structural continuity of the β-sheet structures. Spectroscopic studies confirmed the different molecular arrangements of the two different nanostructures. Furthermore, the smart bolaamphiphile shows a dose-dependent cytotoxicity and cell-proliferation behaviour | ||
| 650 | 4 | |a Journal Article | |
| 700 | 1 | |a Parmar, Hamendra S |e verfasserin |4 aut | |
| 700 | 1 | |a Rasale, Dnyaneshwar B |e verfasserin |4 aut | |
| 700 | 1 | |a Das, Apurba K |e verfasserin |4 aut | |
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