A core outcome set for future endometriosis research : an international consensus development study
© 2020 Royal College of Obstetricians and Gynaecologists..
OBJECTIVE: To develop a core outcome set for endometriosis.
DESIGN: Consensus development study.
SETTING: International.
POPULATION: One hundred and sixteen healthcare professionals, 31 researchers and 206 patient representatives.
METHODS: Modified Delphi method and modified nominal group technique.
RESULTS: The final core outcome set includes three core outcomes for trials evaluating potential treatments for pain and other symptoms associated with endometriosis: overall pain; improvement in the most troublesome symptom; and quality of life. In addition, eight core outcomes for trials evaluating potential treatments for infertility associated with endometriosis were identified: viable intrauterine pregnancy confirmed by ultrasound; pregnancy loss, including ectopic pregnancy, miscarriage, stillbirth and termination of pregnancy; live birth; time to pregnancy leading to live birth; gestational age at delivery; birthweight; neonatal mortality; and major congenital abnormalities. Two core outcomes applicable to all trials were also identified: adverse events and patient satisfaction with treatment.
CONCLUSIONS: Using robust consensus science methods, healthcare professionals, researchers and women with endometriosis have developed a core outcome set to standardise outcome selection, collection and reporting across future randomised controlled trials and systematic reviews evaluating potential treatments for endometriosis. TWEETABLE ABSTRACT: coreoutcomes for future #endometriosis research have been developed @jamesmnduffy.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:127 |
|---|---|
| Enthalten in: |
BJOG : an international journal of obstetrics and gynaecology - 127(2020), 8 vom: 22. Juli, Seite 967-974 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Duffy, Jmn [VerfasserIn] |
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| Links: |
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| Themen: |
Consensus development study |
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| Anmerkungen: |
Date Completed 30.06.2020 Date Revised 23.03.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1111/1471-0528.16157 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM308133579 |
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| 100 | 1 | |a Duffy, Jmn |e verfasserin |4 aut | |
| 245 | 1 | 2 | |a A core outcome set for future endometriosis research |b an international consensus development study |
| 264 | 1 | |c 2020 | |
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| 500 | |a Date Completed 30.06.2020 | ||
| 500 | |a Date Revised 23.03.2022 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2020 Royal College of Obstetricians and Gynaecologists. | ||
| 520 | |a OBJECTIVE: To develop a core outcome set for endometriosis | ||
| 520 | |a DESIGN: Consensus development study | ||
| 520 | |a SETTING: International | ||
| 520 | |a POPULATION: One hundred and sixteen healthcare professionals, 31 researchers and 206 patient representatives | ||
| 520 | |a METHODS: Modified Delphi method and modified nominal group technique | ||
| 520 | |a RESULTS: The final core outcome set includes three core outcomes for trials evaluating potential treatments for pain and other symptoms associated with endometriosis: overall pain; improvement in the most troublesome symptom; and quality of life. In addition, eight core outcomes for trials evaluating potential treatments for infertility associated with endometriosis were identified: viable intrauterine pregnancy confirmed by ultrasound; pregnancy loss, including ectopic pregnancy, miscarriage, stillbirth and termination of pregnancy; live birth; time to pregnancy leading to live birth; gestational age at delivery; birthweight; neonatal mortality; and major congenital abnormalities. Two core outcomes applicable to all trials were also identified: adverse events and patient satisfaction with treatment | ||
| 520 | |a CONCLUSIONS: Using robust consensus science methods, healthcare professionals, researchers and women with endometriosis have developed a core outcome set to standardise outcome selection, collection and reporting across future randomised controlled trials and systematic reviews evaluating potential treatments for endometriosis. TWEETABLE ABSTRACT: coreoutcomes for future #endometriosis research have been developed @jamesmnduffy | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Systematic Review | |
| 650 | 4 | |a Consensus development study | |
| 650 | 4 | |a core outcome set | |
| 650 | 4 | |a endometriosis | |
| 650 | 4 | |a modified Delphi method | |
| 650 | 4 | |a modified nominal group technique | |
| 700 | 1 | |a Hirsch, M |e verfasserin |4 aut | |
| 700 | 1 | |a Vercoe, M |e verfasserin |4 aut | |
| 700 | 1 | |a Abbott, J |e verfasserin |4 aut | |
| 700 | 1 | |a Barker, C |e verfasserin |4 aut | |
| 700 | 1 | |a Collura, B |e verfasserin |4 aut | |
| 700 | 1 | |a Drake, R |e verfasserin |4 aut | |
| 700 | 1 | |a Evers, Jlh |e verfasserin |4 aut | |
| 700 | 1 | |a Hickey, M |e verfasserin |4 aut | |
| 700 | 1 | |a Horne, A W |e verfasserin |4 aut | |
| 700 | 1 | |a Hull, M L |e verfasserin |4 aut | |
| 700 | 1 | |a Kolekar, S |e verfasserin |4 aut | |
| 700 | 1 | |a Lensen, S |e verfasserin |4 aut | |
| 700 | 1 | |a Johnson, N P |e verfasserin |4 aut | |
| 700 | 1 | |a Mahajan, V |e verfasserin |4 aut | |
| 700 | 1 | |a Mol, B W |e verfasserin |4 aut | |
| 700 | 1 | |a Otter, A-S |e verfasserin |4 aut | |
| 700 | 1 | |a Puscasiu, L |e verfasserin |4 aut | |
| 700 | 1 | |a Rodriguez, M B |e verfasserin |4 aut | |
| 700 | 1 | |a Rombauts, L |e verfasserin |4 aut | |
| 700 | 1 | |a Vail, A |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, R |e verfasserin |4 aut | |
| 700 | 1 | |a Farquhar, C M |e verfasserin |4 aut | |
| 700 | 0 | |a endo:outcomes - an International Collaboration Harmonising Outcomes and Outcome Measures for Endometriosis Research |e verfasserin |4 aut | |
| 700 | 1 | |a Daniels, Jane P |e investigator |4 oth | |
| 700 | 1 | |a Lim, Arianne C |e investigator |4 oth | |
| 700 | 1 | |a Edmonds, Katie |e investigator |4 oth | |
| 700 | 1 | |a MacLean, Claire E |e investigator |4 oth | |
| 700 | 1 | |a Appleton, Amy C |e investigator |4 oth | |
| 700 | 1 | |a Skelton, Sarah |e investigator |4 oth | |
| 700 | 1 | |a Byrne, Dominic L |e investigator |4 oth | |
| 700 | 1 | |a White, Rebecca K |e investigator |4 oth | |
| 700 | 1 | |a Sardo, Margarida |e investigator |4 oth | |
| 700 | 1 | |a Fowles, Rebecca C |e investigator |4 oth | |
| 700 | 1 | |a Ata, Baris |e investigator |4 oth | |
| 700 | 1 | |a Richatd, Sarah A |e investigator |4 oth | |
| 700 | 1 | |a Puig Ybanez, Casandra C |e investigator |4 oth | |
| 700 | 1 | |a Peterson, Matthew C |e investigator |4 oth | |
| 700 | 1 | |a Elms, Jasmin L |e investigator |4 oth | |
| 700 | 1 | |a Parks, Ann |e investigator |4 oth | |
| 700 | 1 | |a De Bie Rocks, Bianca L F |e investigator |4 oth | |
| 700 | 1 | |a Roe, Jodie C |e investigator |4 oth | |
| 700 | 1 | |a Doran, Ruby |e investigator |4 oth | |
| 700 | 1 | |a Ceccaroni, Marcello |e investigator |4 oth | |
| 700 | 1 | |a Ferreira, Ceu A |e investigator |4 oth | |
| 700 | 1 | |a Dias, Sofia |e investigator |4 oth | |
| 700 | 1 | |a Pinnington, Tracey |e investigator |4 oth | |
| 700 | 1 | |a Laupa-Santiago, Paula |e investigator |4 oth | |
| 700 | 1 | |a Turner, Marie C |e investigator |4 oth | |
| 700 | 1 | |a Schreurs, Anneke M F |e investigator |4 oth | |
| 700 | 1 | |a Baggot, Eleanor |e investigator |4 oth | |
| 700 | 1 | |a Socolov, Razvan V |e investigator |4 oth | |
| 700 | 1 | |a Yossry, Menem |e investigator |4 oth | |
| 700 | 1 | |a Hodges, Tania M |e investigator |4 oth | |
| 700 | 1 | |a Barbossa, Marina W P |e investigator |4 oth | |
| 700 | 1 | |a Mures, Târgu |e investigator |4 oth | |
| 700 | 1 | |a Lytwyn, Tracy L |e investigator |4 oth | |
| 700 | 1 | |a Egan-Reid, Sophia E L |e investigator |4 oth | |
| 700 | 1 | |a Devlin, Susanna C L |e investigator |4 oth | |
| 700 | 1 | |a Crees, Kira S |e investigator |4 oth | |
| 700 | 1 | |a Baldwin, Bethany C |e investigator |4 oth | |
| 700 | 1 | |a Scott, James R |e investigator |4 oth | |
| 700 | 1 | |a Gravolin, Amy K |e investigator |4 oth | |
| 700 | 1 | |a Chapman, Errin F |e investigator |4 oth | |
| 700 | 1 | |a Bartley, Stephanie N |e investigator |4 oth | |
| 700 | 1 | |a Hamilton, Alicia J |e investigator |4 oth | |
| 700 | 1 | |a Thorpe, Kirstie J |e investigator |4 oth | |
| 700 | 1 | |a Carmody, Denise M |e investigator |4 oth | |
| 700 | 1 | |a Eyeson, Joanna |e investigator |4 oth | |
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| 700 | 1 | |a Henry, Jo |e investigator |4 oth | |
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| 700 | 1 | |a Cummings, Presley Y F V |e investigator |4 oth | |
| 700 | 1 | |a Cook, Lisa A |e investigator |4 oth | |
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