3D Hydrogen Titanate Nanotubes on Ti Foil : A Carrier for Enzymatic Glucose Biosensor

Glucose oxidase (GOx) based biosensors are commercialized and marketed for the high selectivity of GOx. Incorporation nanomaterials with GOx can increase the sensitivity performance. In this work, an enzyme glucose biosensor based on nanotubes was fabricated. By using Ti foil as a carrier, hydrogen titanate nanotubes (HTNTs), which present fine 3D structure with vast pores, were fabricated in-situ by the hydrothermal treatment. The multilayer nanotubes are open-ended with a diameter of 10 nm. Then glucose oxidase (GOx) was loaded on the nanotubes by cross-linking to form an electrode of the amperometric glucose biosensor (GOx/HTNTs/Ti electrode). The fabricated GOx/HTNTs/Ti electrode had a linear response to 1-10 mM glucose, and the response time was 1.5 s. The sensitivity of the biosensor was 1.541 μA·mM-1·cm-2, and the detection limit (S/N = 3) was 59 μM. Obtained results indicate that the in-situ fabrication and unique 3D structure of GOx/HTNTs/Ti electrode are beneficial for its sensitivity.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:20

Enthalten in:

Sensors (Basel, Switzerland) - 20(2020), 4 vom: 14. Feb.

Sprache:

Englisch

Beteiligte Personen:

Ma, Lulu [VerfasserIn]
Yue, Zhao [VerfasserIn]
Huo, Guona [VerfasserIn]
Zhang, Shasha [VerfasserIn]
Zhu, Baolin [VerfasserIn]
Zhang, Shoumin [VerfasserIn]
Huang, Weiping [VerfasserIn]

Links:

Volltext

Themen:

3D structure
7YNJ3PO35Z
D1JT611TNE
EC 1.1.3.4
Glucose
Glucose Oxidase
Glucose biosensor
Glucose oxidase
Hydrogen
Hydrogen titanate nanotubes
IY9XDZ35W2
Journal Article
Nanotubes, Carbon
Ti foil
Titanium

Anmerkungen:

Date Completed 16.10.2020

Date Revised 28.03.2024

published: Electronic

Citation Status MEDLINE

doi:

10.3390/s20041024

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM306688700