Pharmacogenomics : An evolving clinical tool for precision medicine

Copyright © 2020 The Cleveland Clinic Foundation. All Rights Reserved..

Pharmacogenomics, ie, the study of how an individual's genomic profile influences his or her response to drugs, has emerged as a clinical tool to optimize drug therapy. Certain variants in some genes increase the risk of severe, life-threatening adverse effects from certain drugs. Integrating pharmacogenomics into clinical practice to assist in drug selection and dosing has the potential to improve the outcomes of treatment, reduce the risk of drug-induced morbidity and death, and be cost-effective.

Errataetall:

CommentIn: Cleve Clin J Med. 2020 Feb;87(2):71-72. - PMID 32015054

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:87

Enthalten in:

Cleveland Clinic journal of medicine - 87(2020), 2 vom: 03. Feb., Seite 91-99

Sprache:

Englisch

Beteiligte Personen:

Hockings, Jennifer K [VerfasserIn]
Pasternak, Amy L [VerfasserIn]
Erwin, Angelika L [VerfasserIn]
Mason, Neil T [VerfasserIn]
Eng, Charis [VerfasserIn]
Hicks, J Kevin [VerfasserIn]

Links:

Volltext

Themen:

A74586SNO7
Antidepressive Agents, Tricyclic
CYP2C19 protein, human
Clopidogrel
Codeine
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP2D6
EC 1.14.14.1
Journal Article
Review
Serotonin Uptake Inhibitors
UX6OWY2V7J

Anmerkungen:

Date Completed 16.11.2020

Date Revised 07.12.2022

published: Print

CommentIn: Cleve Clin J Med. 2020 Feb;87(2):71-72. - PMID 32015054

Citation Status MEDLINE

doi:

10.3949/ccjm.87a.19073

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM306105780