Unwinding 20 Years of the Archaeal Minichromosome Maintenance Helicase

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Replicative DNA helicases are essential cellular enzymes that unwind duplex DNA in front of the replication fork during chromosomal DNA replication. Replicative helicases were discovered, beginning in the 1970s, in bacteria, bacteriophages, viruses, and eukarya, and, in the mid-1990s, in archaea. This year marks the 20th anniversary of the first report on the archaeal replicative helicase, the minichromosome maintenance (MCM) protein. This minireview summarizes 2 decades of work on the archaeal MCM.

Medienart:

E-Artikel

Erscheinungsjahr:

2020

Erschienen:

2020

Enthalten in:

Zur Gesamtaufnahme - volume:202

Enthalten in:

Journal of bacteriology - 202(2020), 6 vom: 25. Feb.

Sprache:

Englisch

Beteiligte Personen:

Kelman, Lori M [VerfasserIn]
O'Dell, William B [VerfasserIn]
Kelman, Zvi [VerfasserIn]

Links:

Volltext

Themen:

Archaea
Archaeal Proteins
DNA, Archaeal
DNA replication
EC 3.6.4.12
Helicase
Historical Article
Journal Article
MCM
Minichromosome Maintenance Proteins
Minichromosome maintenance
Review
Three-dimensional structure

Anmerkungen:

Date Completed 20.10.2020

Date Revised 20.10.2020

published: Electronic-Print

Citation Status MEDLINE

doi:

10.1128/JB.00729-19

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM305067125