Prognostic value of 18F-FDG PET/CT parameters and histopathologic variables in head and neck cancer
Copyright © 2019 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved..
INTRODUCTION: 18F-fluorodeoxyglucose positron emission tomography/computed tomography parameters such as; maximum standardized uptake values, standard metabolic tumor volume and otal lesion glycosis are important prognostic biomarkers in cancers.
OBJECTIVE: To investigate the prognostic value of these parameters in patients with head and neck cancers.
METHODS: We performed a retrospective study including 47 patients with head and neck cancer who underwent18F-fluorodeoxyglucose positron emission tomography/computed tomography prior to treatment. Standard metabolic tumor volume, otal lesion glycosis and standardized uptake were measured for each patient. The prognostic value of quantitative 18F-fluorodeoxyglucose positron emission tomography/computed tomography parameters and clinicopathologic variables on disease free survival and overall survival were analyzed.
RESULTS: The median (range) standard metabolic tumor volume and otal lesion glycosis and standardized uptake were 7.63cm3 (0.6-34.3), 68.9g (2.58-524.5g), 13.89 (4.89-33.03g/mL), respectively. Lymph node metastases and tumour differentiation were significant variables for disease free survival and overall survival, however, all 18F-fluorodeoxyglucose positron emission tomography/computed tomography parameters were not associated with disease- free survival and overall survival.
CONCLUSION: Pretreatment quantities positron emission tomography parameters did not predict survival in head and neck cancer.
Medienart: |
E-Artikel |
---|
Erscheinungsjahr: |
2021 |
---|---|
Erschienen: |
2021 |
Enthalten in: |
Zur Gesamtaufnahme - volume:87 |
---|---|
Enthalten in: |
Brazilian journal of otorhinolaryngology - 87(2021), 4 vom: 15. Juli, Seite 452-456 |
Sprache: |
Englisch |
---|
Beteiligte Personen: |
Aslan, Hale [VerfasserIn] |
---|
Links: |
---|
Themen: |
0Z5B2CJX4D |
---|
Anmerkungen: |
Date Completed 20.07.2021 Date Revised 02.09.2022 published: Print-Electronic Citation Status MEDLINE |
---|
doi: |
10.1016/j.bjorl.2019.10.014 |
---|
funding: |
|
---|---|
Förderinstitution / Projekttitel: |
|
PPN (Katalog-ID): |
NLM304987328 |
---|
LEADER | 01000naa a22002652 4500 | ||
---|---|---|---|
001 | NLM304987328 | ||
003 | DE-627 | ||
005 | 20231225120156.0 | ||
007 | cr uuu---uuuuu | ||
008 | 231225s2021 xx |||||o 00| ||eng c | ||
024 | 7 | |a 10.1016/j.bjorl.2019.10.014 |2 doi | |
028 | 5 | 2 | |a pubmed24n1016.xml |
035 | |a (DE-627)NLM304987328 | ||
035 | |a (NLM)31899125 | ||
035 | |a (PII)S1808-8694(19)30151-X | ||
040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
041 | |a eng | ||
100 | 1 | |a Aslan, Hale |e verfasserin |4 aut | |
245 | 1 | 0 | |a Prognostic value of 18F-FDG PET/CT parameters and histopathologic variables in head and neck cancer |
264 | 1 | |c 2021 | |
336 | |a Text |b txt |2 rdacontent | ||
337 | |a ƒaComputermedien |b c |2 rdamedia | ||
338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
500 | |a Date Completed 20.07.2021 | ||
500 | |a Date Revised 02.09.2022 | ||
500 | |a published: Print-Electronic | ||
500 | |a Citation Status MEDLINE | ||
520 | |a Copyright © 2019 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved. | ||
520 | |a INTRODUCTION: 18F-fluorodeoxyglucose positron emission tomography/computed tomography parameters such as; maximum standardized uptake values, standard metabolic tumor volume and otal lesion glycosis are important prognostic biomarkers in cancers | ||
520 | |a OBJECTIVE: To investigate the prognostic value of these parameters in patients with head and neck cancers | ||
520 | |a METHODS: We performed a retrospective study including 47 patients with head and neck cancer who underwent18F-fluorodeoxyglucose positron emission tomography/computed tomography prior to treatment. Standard metabolic tumor volume, otal lesion glycosis and standardized uptake were measured for each patient. The prognostic value of quantitative 18F-fluorodeoxyglucose positron emission tomography/computed tomography parameters and clinicopathologic variables on disease free survival and overall survival were analyzed | ||
520 | |a RESULTS: The median (range) standard metabolic tumor volume and otal lesion glycosis and standardized uptake were 7.63cm3 (0.6-34.3), 68.9g (2.58-524.5g), 13.89 (4.89-33.03g/mL), respectively. Lymph node metastases and tumour differentiation were significant variables for disease free survival and overall survival, however, all 18F-fluorodeoxyglucose positron emission tomography/computed tomography parameters were not associated with disease- free survival and overall survival | ||
520 | |a CONCLUSION: Pretreatment quantities positron emission tomography parameters did not predict survival in head and neck cancer | ||
650 | 4 | |a Journal Article | |
650 | 4 | |a Head and neck cancer (18)F-FDG PET/CT | |
650 | 4 | |a Metabolic parameters | |
650 | 4 | |a Prognosis | |
650 | 7 | |a Fluorodeoxyglucose F18 |2 NLM | |
650 | 7 | |a 0Z5B2CJX4D |2 NLM | |
700 | 1 | |a Cekin, Gul |e verfasserin |4 aut | |
700 | 1 | |a Pinar, Ercan |e verfasserin |4 aut | |
700 | 1 | |a Yazir, Mustafa |e verfasserin |4 aut | |
700 | 1 | |a Imre, Abdulkadir |e verfasserin |4 aut | |
700 | 1 | |a Songu, Murat |e verfasserin |4 aut | |
700 | 1 | |a Islek, Akif |e verfasserin |4 aut | |
700 | 1 | |a Aladag, Ibrahim |e verfasserin |4 aut | |
700 | 1 | |a Oncel, Ismail Semih |e verfasserin |4 aut | |
773 | 0 | 8 | |i Enthalten in |t Brazilian journal of otorhinolaryngology |d 2005 |g 87(2021), 4 vom: 15. Juli, Seite 452-456 |w (DE-627)NLM160421748 |x 1808-8686 |7 nnns |
773 | 1 | 8 | |g volume:87 |g year:2021 |g number:4 |g day:15 |g month:07 |g pages:452-456 |
856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.bjorl.2019.10.014 |3 Volltext |
912 | |a GBV_USEFLAG_A | ||
912 | |a GBV_NLM | ||
951 | |a AR | ||
952 | |d 87 |j 2021 |e 4 |b 15 |c 07 |h 452-456 |