Facile Synthesis of ZnMn2O4rGO Microspheres for Ultrasensitive Electrochemical Detection of Hydrogen Peroxide from Human Breast Cancer Cells
Mixed transition-metal oxides have witnessed increasing attention in catalysts and electrocatalysts. Herein, reduced graphene oxide-wrapped ZnMn2O4 microspheres (ZnMn2O4rGO) were facilely synthesized through the solvothermal technique. The microstructure and morphology of ZnMn2O4@rGO microspheres were analyzed under Raman, X-ray photoelectron, X-ray diffraction, and energy-dispersive spectroscopies and scanning electron microscopy. The synthesized ZnMn2O4@rGO was employed as an excellent electrocatalyst for the reduction of hydrogen peroxide (H2O2). The ZnMn2O4@rGO-modified glassy carbon electrode (ZnMn2O4@rGO/GCE) exhibited a linear detection to H2O2 in a wide concentration range of 0.03-6000 μM with a detection limit of 0.012 μM. The biosensor was evaluated to determine H2O2 secreted by human breast cancer cells (MCF-7), indicating its promising applications in physiology and diagnosis.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2020 |
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| Erschienen: |
2020 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:12 |
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| Enthalten in: |
ACS applied materials & interfaces - 12(2020), 3 vom: 22. Jan., Seite 3430-3437 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Li, Yuanyuan [VerfasserIn] |
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| Links: |
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| Themen: |
7782-42-5 |
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| Anmerkungen: |
Date Completed 19.10.2020 Date Revised 19.10.2020 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1021/acsami.9b19126 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM304770973 |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Mixed transition-metal oxides have witnessed increasing attention in catalysts and electrocatalysts. Herein, reduced graphene oxide-wrapped ZnMn2O4 microspheres (ZnMn2O4rGO) were facilely synthesized through the solvothermal technique. The microstructure and morphology of ZnMn2O4@rGO microspheres were analyzed under Raman, X-ray photoelectron, X-ray diffraction, and energy-dispersive spectroscopies and scanning electron microscopy. The synthesized ZnMn2O4@rGO was employed as an excellent electrocatalyst for the reduction of hydrogen peroxide (H2O2). The ZnMn2O4@rGO-modified glassy carbon electrode (ZnMn2O4@rGO/GCE) exhibited a linear detection to H2O2 in a wide concentration range of 0.03-6000 μM with a detection limit of 0.012 μM. The biosensor was evaluated to determine H2O2 secreted by human breast cancer cells (MCF-7), indicating its promising applications in physiology and diagnosis | ||
| 650 | 4 | |a Evaluation Study | |
| 650 | 4 | |a Journal Article | |
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| 650 | 4 | |a breast cancer cells | |
| 650 | 4 | |a electrochemical sensor | |
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| 700 | 1 | |a Tang, Li |e verfasserin |4 aut | |
| 700 | 1 | |a Wang, Jinhua |e verfasserin |4 aut | |
| 700 | 1 | |a Luo, Liqiang |e verfasserin |4 aut | |
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