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Thiazole in the targeted anticancer drug discovery

Cancer is known as one of the main causes of death in the world; and many compounds have been synthesized to date with potential use in cancer therapy. Thiazole is a versatile heterocycle, found in the structure of many drugs in use as well as anticancer agents. This review provides an overview of recent advances in thiazole-bearing compounds as anticancer agents with particular emphasis on their mechanism of action in cancerous cells. Chemical designs, structure-activity relationships and relevant preclinical properties have been comprehensively described

Year of Publication: 2019
Contained in: Future medicinal chemistry Vol. 11, No. 15 (2019), p. 1929-1952
All journal articles: Search for all articles in this journal
Language: English
Contributors: Ayati, Adileh | Author
Emami, Saeed
Moghimi, Setareh
Foroumadi, Alireza
Full text access:
Electronic availability is being checked...
Links: Full Text (dx.doi.org)
Keywords: Journal Article
anticancer agents
cancer
drug discovery
signaling pathways
thiazole
tumor cells
ISSN: 1756-8927
Note: Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Notes: Date Revised 13.09.2019
published: Print-Electronic
Citation Status In-Data-Review
Copyright: From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Physical Description: Online-Ressource
ID (e.g. DOI, URN): 10.4155/fmc-2018-0416
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