Casein-derived peptides as an alternative ingredient for low-phenylalanine diets

INTRODUCTION: Introduction: casein-derived peptides can be liberated both in vivo via normal digestion of casein, as well as in vitro via enzymatic hydrolysis. These peptides were suggested to have biological activity. Objectives: the aim of this study was to describe the production and characterization of casein peptides and to explore the potential of these peptides as an option for low-phenylalanine diets. Methods: peptides were produced by tryptic hydrolysis of sodium caseinate and acid precipitation with HCl, followed by precipitation with ethanol or aggregation of CaCl2 or ZnSO4. Results: the amino acid analysis revealed a significant reduction in the amount of phenylalanine from the original protein. Conclusion: casein-derived peptides could be a future alternative of short chain peptides to low-phenylalanine formulations.

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:36

Enthalten in:

Nutricion hospitalaria - 36(2019), 3 vom: 01. Juli, Seite 718-722

Sprache:

Englisch

Weiterer Titel:

Péptidos derivados de la caseína como ingrediente alternativo para las dietas bajas en fenilalanina

Beteiligte Personen:

Krüger, Claudia C H [VerfasserIn]
Azevedo, Thaise D [VerfasserIn]
Piltz, Marina Talamini [VerfasserIn]
Silva, Ágatha Transfeld [VerfasserIn]
Cândido, Lys Mary Bileski [VerfasserIn]

Links:

Volltext

Themen:

47E5O17Y3R
Amino Acids
Caseína. Péptidos. Fenilalanina. Fenilcetonuria.
Caseins
Journal Article
Peptides
Phenylalanine

Anmerkungen:

Date Completed 06.01.2020

Date Revised 09.04.2022

published: Print

Citation Status MEDLINE

doi:

10.20960/nh.2391

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM295801964