Cartilage wear patterns in severe osteoarthritis of the trapeziometacarpal joint : a quantitative analysis
Copyright © 2019 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved..
OBJECTIVE: The present quantitative study aimed to assess the three-dimensional (3-D) cartilage wear patterns of the first metacarpal and trapezium in the advanced stage of osteoarthritis (OA) and compare cartilage measurements with radiographic severity.
DESIGN: Using 19 cadaveric trapeziometacarpal (TMC) joints, 3-D cartilage surface models of the first metacarpal and trapezium were created with a laser scanner, and 3-D bone surface model counterparts were similarly created after dissolving the cartilage. These two models were superimposed, and the interval distance on the articular surface as the cartilage thickness was measured. All measurements were obtained in categorized anatomic regions on the articular surface of the respective bone, and we analyzed the 3-D wear patterns on the entire cartilage surface. Furthermore, we compared measurements of cartilage thickness with radiographic OA severity according to the Eaton grading system using Pearson correlation coefficients (r).
RESULTS: In the first metacarpal, the cartilage thickness declined volarly (the mean cartilage thickness of the volar region was 0.32 ± 0.16 mm, whereas that of the dorsal region was 0.53 ± 0.18 mm). Conversely, the cartilage evenly degenerated throughout the articular surface of the trapezium. Measurements of the categorized regions where cartilage thinning was remarkable exhibited statistical correlations with radiographic staging (r = -0.48 to -0.72).
CONCLUSIONS: Our findings indicate that cartilage wear patterns differ between the first metacarpal and trapezium in the late stage of OA. There is a need for further studies on cartilage degeneration leading to symptomatic OA in the TMC joint.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019 |
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| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:27 |
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| Enthalten in: |
Osteoarthritis and cartilage - 27(2019), 8 vom: 26. Aug., Seite 1152-1162 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Miyamura, S [VerfasserIn] |
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| Links: |
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| Themen: |
Cartilage wear |
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| Anmerkungen: |
Date Completed 25.08.2020 Date Revised 25.08.2020 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1016/j.joca.2019.03.006 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM295761121 |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2019 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved. | ||
| 520 | |a OBJECTIVE: The present quantitative study aimed to assess the three-dimensional (3-D) cartilage wear patterns of the first metacarpal and trapezium in the advanced stage of osteoarthritis (OA) and compare cartilage measurements with radiographic severity | ||
| 520 | |a DESIGN: Using 19 cadaveric trapeziometacarpal (TMC) joints, 3-D cartilage surface models of the first metacarpal and trapezium were created with a laser scanner, and 3-D bone surface model counterparts were similarly created after dissolving the cartilage. These two models were superimposed, and the interval distance on the articular surface as the cartilage thickness was measured. All measurements were obtained in categorized anatomic regions on the articular surface of the respective bone, and we analyzed the 3-D wear patterns on the entire cartilage surface. Furthermore, we compared measurements of cartilage thickness with radiographic OA severity according to the Eaton grading system using Pearson correlation coefficients (r) | ||
| 520 | |a RESULTS: In the first metacarpal, the cartilage thickness declined volarly (the mean cartilage thickness of the volar region was 0.32 ± 0.16 mm, whereas that of the dorsal region was 0.53 ± 0.18 mm). Conversely, the cartilage evenly degenerated throughout the articular surface of the trapezium. Measurements of the categorized regions where cartilage thinning was remarkable exhibited statistical correlations with radiographic staging (r = -0.48 to -0.72) | ||
| 520 | |a CONCLUSIONS: Our findings indicate that cartilage wear patterns differ between the first metacarpal and trapezium in the late stage of OA. There is a need for further studies on cartilage degeneration leading to symptomatic OA in the TMC joint | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Research Support, Non-U.S. Gov't | |
| 650 | 4 | |a Cartilage wear | |
| 650 | 4 | |a First metacarpal | |
| 650 | 4 | |a Laser scanner | |
| 650 | 4 | |a Osteoarthritis | |
| 650 | 4 | |a Trapeziometacarpal joint | |
| 650 | 4 | |a Trapezium | |
| 700 | 1 | |a Oka, K |e verfasserin |4 aut | |
| 700 | 1 | |a Sakai, T |e verfasserin |4 aut | |
| 700 | 1 | |a Tanaka, H |e verfasserin |4 aut | |
| 700 | 1 | |a Shiode, R |e verfasserin |4 aut | |
| 700 | 1 | |a Shimada, S |e verfasserin |4 aut | |
| 700 | 1 | |a Mae, T |e verfasserin |4 aut | |
| 700 | 1 | |a Sugamoto, K |e verfasserin |4 aut | |
| 700 | 1 | |a Yoshikawa, H |e verfasserin |4 aut | |
| 700 | 1 | |a Murase, T |e verfasserin |4 aut | |
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