A fluvoxamine-related fatality : Case report with postmortem concentrations

Copyright © 2019 Elsevier B.V. All rights reserved..

Fluvoxamine is a selective serotonin reuptake inhibitor that has been considered relatively safe in overdose. At therapeutic and supratherapeutic concentrations, fluvoxamine affects cardiac conduction, prolongs QTc interval, causes hypotension, obtundation, and can increase propensity for seizures. A man in his 60s was found dead at his home with a postmortem fluvoxamine peripheral blood concentration of 4.9 mg/L, and a liver concentration of 440 mg/kg. His cause of death was determined to be acute fluvoxamine toxicity.

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:300

Enthalten in:

Forensic science international - 300(2019) vom: 11. Juli, Seite e31-e33

Sprache:

Englisch

Beteiligte Personen:

Otter, Jenna [VerfasserIn]
McIntyre, Iain M [VerfasserIn]
Morhaime, Jacquelyn [VerfasserIn]
Cantrell, Lee [VerfasserIn]

Links:

Volltext

Themen:

Case Reports
Fluvoxamine
Journal Article
O4L1XPO44W
Overdose
Postmortem concentration
SSRI
Serotonin Uptake Inhibitors

Anmerkungen:

Date Completed 17.06.2019

Date Revised 07.12.2022

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.forsciint.2019.02.047

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM294948147