Continuous spike-waves during slow-wave sleep : Experience during 20 years
Copyright © 2019 Asociación Española de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved..
INTRODUCTION: Continuous spikes and waves during slow sleep (CSWS) is an EEG pattern that appears during childhood, and is often associated with cognitive impairment. It can appear in the course of epileptic syndromes, as well as in benign epilepsy. The aim of this study is to analyse epidemiological and clinical characteristic of patients with CSWS, in order to describe possible predictive factors in their outcome.
METHODS: A retrospective study was conducted on paediatric patients with CSWS treated in a third-level hospital from November 1997 to November 2017.
RESULTS: The study included 25 patients (68% male), of whom 76% had abnormalities in the neuroimaging or suffered from psychomotor development disorder (secondary CSWS). The rest were healthy, or diagnosed with idiopathic epilepsy. The mean age of onset of CSWS was 6.7 years, but earlier in the secondary CSWS cases. Symptoms were present during the CSWS episode in 72% of cases. All of them were treated with antiepileptic drugs, which were effective in 36%. CSWS stopped in 72%, and remission was longer if the CSWS onset occurred at an older age. One-third (33%) presented with sequelae, mostly cognitive and behavioural alterations. Outcome was poorer in those with secondary CSWS and, in those whose CSWS started at an earlier age and lasted longer.
CONCLUSION: The CSWS pattern, although rare, is still a therapeutic challenge. A close follow-up of the patients with epilepsy is important, especially if associated with cognitive impairment, in order to establish an early diagnosis and treatment.
| Medienart: |
E-Artikel |
|---|
| Erscheinungsjahr: |
2019 |
|---|---|
| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:91 |
|---|---|
| Enthalten in: |
Anales de pediatria - 91(2019), 3 vom: 01. Sept., Seite 180-188 |
| Sprache: |
Spanisch |
|---|
| Weiterer Titel: |
Patrón punta-onda continua en el sueño lento: nuestra experiencia durante 20 años |
|---|
| Beteiligte Personen: |
Escobar Fernández, Laura [VerfasserIn] |
|---|
| Links: |
|---|
| Anmerkungen: |
Date Completed 06.02.2020 Date Revised 19.05.2021 published: Print-Electronic Citation Status MEDLINE |
|---|
| doi: |
10.1016/j.anpedi.2018.12.016 |
|---|
| funding: |
|
|---|---|
| Förderinstitution / Projekttitel: |
|
| PPN (Katalog-ID): |
NLM293976813 |
|---|
| LEADER | 01000naa a22002652 4500 | ||
|---|---|---|---|
| 001 | NLM293976813 | ||
| 003 | DE-627 | ||
| 005 | 20231225080505.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231225s2019 xx |||||o 00| ||spa c | ||
| 024 | 7 | |a 10.1016/j.anpedi.2018.12.016 |2 doi | |
| 028 | 5 | 2 | |a pubmed24n0979.xml |
| 035 | |a (DE-627)NLM293976813 | ||
| 035 | |a (NLM)30772272 | ||
| 035 | |a (PII)S1695-4033(19)30021-9 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rakwb | ||
| 041 | |a spa | ||
| 100 | 1 | |a Escobar Fernández, Laura |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Continuous spike-waves during slow-wave sleep |b Experience during 20 years |
| 246 | 3 | 3 | |a Patrón punta-onda continua en el sueño lento: nuestra experiencia durante 20 años |
| 264 | 1 | |c 2019 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 06.02.2020 | ||
| 500 | |a Date Revised 19.05.2021 | ||
| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2019 Asociación Española de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved. | ||
| 520 | |a INTRODUCTION: Continuous spikes and waves during slow sleep (CSWS) is an EEG pattern that appears during childhood, and is often associated with cognitive impairment. It can appear in the course of epileptic syndromes, as well as in benign epilepsy. The aim of this study is to analyse epidemiological and clinical characteristic of patients with CSWS, in order to describe possible predictive factors in their outcome | ||
| 520 | |a METHODS: A retrospective study was conducted on paediatric patients with CSWS treated in a third-level hospital from November 1997 to November 2017 | ||
| 520 | |a RESULTS: The study included 25 patients (68% male), of whom 76% had abnormalities in the neuroimaging or suffered from psychomotor development disorder (secondary CSWS). The rest were healthy, or diagnosed with idiopathic epilepsy. The mean age of onset of CSWS was 6.7 years, but earlier in the secondary CSWS cases. Symptoms were present during the CSWS episode in 72% of cases. All of them were treated with antiepileptic drugs, which were effective in 36%. CSWS stopped in 72%, and remission was longer if the CSWS onset occurred at an older age. One-third (33%) presented with sequelae, mostly cognitive and behavioural alterations. Outcome was poorer in those with secondary CSWS and, in those whose CSWS started at an earlier age and lasted longer | ||
| 520 | |a CONCLUSION: The CSWS pattern, although rare, is still a therapeutic challenge. A close follow-up of the patients with epilepsy is important, especially if associated with cognitive impairment, in order to establish an early diagnosis and treatment | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Observational Study | |
| 650 | 4 | |a Continuous spike-waves during sleep | |
| 650 | 4 | |a Electrical status epilepticus during slow wave sleep | |
| 650 | 4 | |a Electroencefalograma | |
| 650 | 4 | |a Electroencephalogram | |
| 650 | 4 | |a Epilepsia rolándica | |
| 650 | 4 | |a Estado epiléptico durante el sueño | |
| 650 | 4 | |a Landau-Kleffner syndrome | |
| 650 | 4 | |a Punta-onda continua durante el sueño lento | |
| 650 | 4 | |a Rolandic epilepsy | |
| 650 | 4 | |a Síndrome Landau-Kleffner | |
| 650 | 7 | |a Anticonvulsants |2 NLM | |
| 700 | 1 | |a Coccolo Góngora, Alejandra |e verfasserin |4 aut | |
| 700 | 1 | |a Vázquez López, María |e verfasserin |4 aut | |
| 700 | 1 | |a Polo Arrondo, Ana Paloma |e verfasserin |4 aut | |
| 700 | 1 | |a Miranda Herrero, María Concepción |e verfasserin |4 aut | |
| 700 | 1 | |a Barredo Valderrama, Estíbaliz |e verfasserin |4 aut | |
| 700 | 1 | |a Castro de Castro, Pedro |e verfasserin |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Anales de pediatria |d 2010 |g 91(2019), 3 vom: 01. Sept., Seite 180-188 |w (DE-627)NLM19488628X |x 2341-2879 |7 nnns |
| 773 | 1 | 8 | |g volume:91 |g year:2019 |g number:3 |g day:01 |g month:09 |g pages:180-188 |
| 856 | 4 | 0 | |u http://dx.doi.org/10.1016/j.anpedi.2018.12.016 |3 Volltext |
| 912 | |a GBV_USEFLAG_A | ||
| 912 | |a GBV_NLM | ||
| 951 | |a AR | ||
| 952 | |d 91 |j 2019 |e 3 |b 01 |c 09 |h 180-188 | ||