Removal capacity of different high-flux dialyzers during postdilution online hemodiafiltration
© 2018 International Society for Hemodialysis..
INTRODUCTION: The aim of this study is to compare molecule removal and albumin leakage in postdilution online hemodiafiltration with different high-flux dialyzers.
METHODS: We studied seven high-flux dialyzers (Polyflux 210H®, Evodial 2.2®, FxCordiax1000®, Elisio21H®, TS-2.1SL®, XevontaHi20®, VitaPES 210-HF®) in 6 patients. The reduction ratio (RR) of small- and middle-sized molecules was calculated. Dialysate samples were collected to estimate the albumin leakage.
FINDINGS: Global differences between dialyzers were observed in the RR of ß2 microglobulin (P =0.003) and prolactin (P =0.013). The mean loss of albumin in the dialysate per session varied between 114 ± 67 mg (with Evodial 2.2) and 2621 ± 1363 mg per session (with XevontaHi20). We found global differences between dialyzers in total albumin loss (P = 0.05).
DISCUSSION: We demonstrated that the performance of high-flux dialyzers was different among the types and that not all high-flux dialyzers should be considered equal.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2019 |
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| Erschienen: |
2019 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:23 |
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| Enthalten in: |
Hemodialysis international. International Symposium on Home Hemodialysis - 23(2019), 1 vom: 27. Jan., Seite 50-57 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Santos García, Alba [VerfasserIn] |
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| Links: |
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| Themen: |
Albumin loss |
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| Anmerkungen: |
Date Completed 10.06.2020 Date Revised 10.06.2020 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1111/hdi.12685 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM290017122 |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2018 International Society for Hemodialysis. | ||
| 520 | |a INTRODUCTION: The aim of this study is to compare molecule removal and albumin leakage in postdilution online hemodiafiltration with different high-flux dialyzers | ||
| 520 | |a METHODS: We studied seven high-flux dialyzers (Polyflux 210H®, Evodial 2.2®, FxCordiax1000®, Elisio21H®, TS-2.1SL®, XevontaHi20®, VitaPES 210-HF®) in 6 patients. The reduction ratio (RR) of small- and middle-sized molecules was calculated. Dialysate samples were collected to estimate the albumin leakage | ||
| 520 | |a FINDINGS: Global differences between dialyzers were observed in the RR of ß2 microglobulin (P =0.003) and prolactin (P =0.013). The mean loss of albumin in the dialysate per session varied between 114 ± 67 mg (with Evodial 2.2) and 2621 ± 1363 mg per session (with XevontaHi20). We found global differences between dialyzers in total albumin loss (P = 0.05) | ||
| 520 | |a DISCUSSION: We demonstrated that the performance of high-flux dialyzers was different among the types and that not all high-flux dialyzers should be considered equal | ||
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a albumin loss | |
| 650 | 4 | |a dialyzer performance | |
| 650 | 4 | |a hemodiafiltration | |
| 650 | 4 | |a high-flux membrane | |
| 650 | 4 | |a middle-sized molecule clearance | |
| 650 | 7 | |a Dialysis Solutions |2 NLM | |
| 700 | 1 | |a Macías Carmona, Nicolás |e verfasserin |4 aut | |
| 700 | 1 | |a Vega Martínez, Almudena |e verfasserin |4 aut | |
| 700 | 1 | |a Abad Estébanez, Soraya |e verfasserin |4 aut | |
| 700 | 1 | |a Linares Grávalos, Tania |e verfasserin |4 aut | |
| 700 | 1 | |a Aragoncillo Sauco, Inés |e verfasserin |4 aut | |
| 700 | 1 | |a Verdalles Guzmán, Ursula |e verfasserin |4 aut | |
| 700 | 1 | |a Panizo González, Nayara |e verfasserin |4 aut | |
| 700 | 1 | |a Cruzado Vega, Leonidas |e verfasserin |4 aut | |
| 700 | 1 | |a López Gómez, Juan Manuel |e verfasserin |4 aut | |
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