Surgery for Endometriosis Improves Major Domains of Quality of Life : A Systematic Review and Meta-Analysis

Copyright © 2018. Published by Elsevier Inc..

Because surgery for endometriosis can involve severe complications, it is important to determine if the patient's quality of life (QOL) is indeed improved after surgery. A systematic review and meta-analysis, when appropriate, was conducted and included 38 studies that assessed the QOL using validated questionnaires administered before and after surgery. Results were grouped according to the type of endometriosis reported: all types endometriosis, deep infiltrative endometriosis (DIE), and bowel endometriosis. Quantitative analysis was performed on 17 homogeneous studies. Pooled response mean differences between the 36-Item and 12-Item Short Form Survey (SF-36 and SF-12) showed significant improvement in Mental Component Score (MCS) after surgery for all types of endometriosis (.21; 95% confidence interval [CI], .04-.38); significant improvement after surgical treatment for DIE in Vitality (.67; 95% CI, .41-.94), Social Functioning (.59; 95% CI, .18-.99), Role Emotional .49; 95% CI, .02-.97), Mental Health (.39; 95% CI, .03-.74), Physical Functioning (.93; 95% CI, .49-1.38), Bodily Pain (1.23; 95% CI, .47-1.99), General Health (.57; 95% CI, .02-1.12), MCS (.55; 95% CI, .10-1.00), and Physical Component Score (PCS; .73; 95% CI, .27-1.18); and significant improvement after surgery for bowel endometriosis for all 8 domains (Vitality [1.00; 95% CI, .56-1.43], Social Functioning [.97; 95% CI, .57-1.37], Role Emotional [1.17; 95% CI, .7-1.63], Mental Health [.94; 95% CI, .5-1.38], Physical Functioning [.74; 95% CI, .3-1.18], Role Physical [1.25; 95% CI, .75-1.76], Bodily Pain [1.39; 95% CI, .79-1.98], General Health [.84; 95% CI, 1.46-1.22]), MCS (.93; 95% CI, .47-1.40), PCS (.82; 95% CI, .40-1.23), and total score (1.15; 95% CI, .48-1.83). Only 1 study assessed patients with minimal disease and showed significant improvement in PCS (p = .002) and MCS (p <.001). This systematic review reveals that surgery for endometriosis resulted in overall improvement in most health domains of health-related QOL, with the greatest improvement found in the Bodily Pain domain.

Medienart:

E-Artikel

Erscheinungsjahr:

2019

Erschienen:

2019

Enthalten in:

Zur Gesamtaufnahme - volume:26

Enthalten in:

Journal of minimally invasive gynecology - 26(2019), 2 vom: 01. Feb., Seite 266-278

Sprache:

Englisch

Beteiligte Personen:

Arcoverde, Fernanda Vieira Lins [VerfasserIn]
Andres, Marina de Paula [VerfasserIn]
Borrelli, Giuliano Moysés [VerfasserIn]
Barbosa, Priscila de Almeida [VerfasserIn]
Abrão, Mauricio Simões [VerfasserIn]
Kho, Rosanne Marie [VerfasserIn]

Links:

Volltext

Themen:

Bowel endometriosis
Deep infiltrative endometriosis
Endometriosis
Journal Article
Meta-Analysis
Quality of life
Surgical treatment
Systematic Review

Anmerkungen:

Date Completed 19.07.2019

Date Revised 19.07.2019

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1016/j.jmig.2018.09.774

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM288805720