Total Synthesis of Asperphenins A and B
The first total synthesis of asperphenins A and B has been accomplished in a concise, highly stereoselective fashion from commercially available materials (15 steps, 9.7% and 14.2% overall yields, respectively). The convergent route featured the judicious choice of protecting groups, fragment assembly strategy and a late-stage iron-catalyzed Wacker-type selective oxidation of an internal alkene to the corresponding ketone.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:20 |
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| Enthalten in: |
Organic letters - 20(2018), 19 vom: 05. Okt., Seite 6170-6173 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Yan, Jia-Lei [VerfasserIn] |
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| Links: |
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| Themen: |
5TWQ1V240M |
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| Anmerkungen: |
Date Completed 22.10.2019 Date Revised 29.03.2024 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1021/acs.orglett.8b02652 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM288695321 |
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| 500 | |a Citation Status MEDLINE | ||
| 520 | |a The first total synthesis of asperphenins A and B has been accomplished in a concise, highly stereoselective fashion from commercially available materials (15 steps, 9.7% and 14.2% overall yields, respectively). The convergent route featured the judicious choice of protecting groups, fragment assembly strategy and a late-stage iron-catalyzed Wacker-type selective oxidation of an internal alkene to the corresponding ketone | ||
| 650 | 4 | |a Journal Article | |
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| 650 | 7 | |a Amides |2 NLM | |
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| 700 | 1 | |a Cheng, Yingying |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Jing |e verfasserin |4 aut | |
| 700 | 1 | |a Ratnayake, Ranjala |e verfasserin |4 aut | |
| 700 | 1 | |a Dang, Long H |e verfasserin |4 aut | |
| 700 | 1 | |a Luesch, Hendrik |e verfasserin |4 aut | |
| 700 | 1 | |a Guo, Yian |e verfasserin |4 aut | |
| 700 | 1 | |a Ye, Tao |e verfasserin |4 aut | |
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