Eudesmanolides and Other Constituents from the Flowers of Wedelia trilobata
© 2018 Wiley-VHCA AG, Zurich, Switzerland..
Two eudesmane sesquiterpene lactones, wedetrilides B (1) and C (2), along with five known analogues (3 - 8), an ent-kaurane diterpenoid (9), a steroid (10), as well as cinnamic acid derivatives (11 - 13), were isolated from the flowers of Wedelia trilobata. Their structures were elucidated on the basis of extensive spectroscopic analyses and by comparison of their NMR data with those of related compounds. Furthermore, the structures of 1 and 3 - 5 were confirmed by X-ray single-crystal diffraction analyses. Compounds 4 and 5 exhibited weak cytotoxic activities against the MCF-7, HeLa, and A549 cell lines. Compounds 3 - 5 were also evaluated for their inhibitory effects against HIV lytic replication.
| Errataetall: |
ErratumIn: Chem Biodivers. 2020 Oct;17(10):e2000807. - PMID 33112500 |
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| Medienart: |
E-Artikel |
| Erscheinungsjahr: |
2018 |
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| Erschienen: |
2018 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:15 |
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| Enthalten in: |
Chemistry & biodiversity - 15(2018), 3 vom: 26. März, Seite e1700411 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Hui, Yang [VerfasserIn] |
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| Links: |
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| Themen: |
Anti-HIV Agents |
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| Anmerkungen: |
Date Completed 17.04.2018 Date Revised 17.04.2018 published: Print-Electronic ErratumIn: Chem Biodivers. 2020 Oct;17(10):e2000807. - PMID 33112500 Citation Status MEDLINE |
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| doi: |
10.1002/cbdv.201700411 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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NLM280299834 |
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| 520 | |a Two eudesmane sesquiterpene lactones, wedetrilides B (1) and C (2), along with five known analogues (3 - 8), an ent-kaurane diterpenoid (9), a steroid (10), as well as cinnamic acid derivatives (11 - 13), were isolated from the flowers of Wedelia trilobata. Their structures were elucidated on the basis of extensive spectroscopic analyses and by comparison of their NMR data with those of related compounds. Furthermore, the structures of 1 and 3 - 5 were confirmed by X-ray single-crystal diffraction analyses. Compounds 4 and 5 exhibited weak cytotoxic activities against the MCF-7, HeLa, and A549 cell lines. Compounds 3 - 5 were also evaluated for their inhibitory effects against HIV lytic replication | ||
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| 700 | 1 | |a Liu, Ya-Jun |e verfasserin |4 aut | |
| 700 | 1 | |a Han, Chang-Ri |e verfasserin |4 aut | |
| 700 | 1 | |a Song, Xiao-Ping |e verfasserin |4 aut | |
| 700 | 1 | |a Dai, Chun-Yan |e verfasserin |4 aut | |
| 700 | 1 | |a Zhang, Xiao-Peng |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Wen-Hao |e verfasserin |4 aut | |
| 700 | 1 | |a Chen, Guang-Ying |e verfasserin |4 aut | |
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