World Health Organization recommendations for multidrug-resistant tuberculosis : should different standards be applied?

The World Health Organization uses a Grading of Recommendations Assessment, Development, and Evaluation process to make recommendations for treating multidrug-resistant tuberculosis. Even with this standardized approach, there have been discrepancies between recommendations for newer drugs such as bedaquiline and delamanid and the shorter regimen. This may be because newer drugs are novel chemical entities and may merit closer scrutiny. Here, we explore the problematic nature of this supposition, arguing that although the newer drugs have been used in fewer individuals, they may have more robust efficacy and safety data than many of the second-line drugs used in the shorter regimen.

Errataetall:

ErratumIn: Int J Tuberc Lung Dis. 2018 Mar 1;22(3):353-354. - PMID 29471916

Medienart:

E-Artikel

Erscheinungsjahr:

2017

Erschienen:

2017

Enthalten in:

Zur Gesamtaufnahme - volume:21

Enthalten in:

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 21(2017), 12 vom: 01. Dez., Seite 1211-1213

Sprache:

Englisch

Beteiligte Personen:

Cox, V [VerfasserIn]
Furin, J [VerfasserIn]

Links:

Volltext

Themen:

78846I289Y
Antitubercular Agents
Bedaquiline
Diarylquinolines
Journal Article
Nitroimidazoles
OPC-67683
Oxazoles

Anmerkungen:

Date Completed 11.01.2019

Date Revised 11.01.2019

published: Print

ErratumIn: Int J Tuberc Lung Dis. 2018 Mar 1;22(3):353-354. - PMID 29471916

Citation Status MEDLINE

doi:

10.5588/ijtld.17.0199

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM279606494