Single- and double-tunnel endoscopic submucosal tunnel dissection for large superficial esophageal squamous cell neoplasms

© Georg Thieme Verlag KG Stuttgart · New York..

BACKGROUND AND STUDY AIM: Single-tunnel endoscopic submucosal tunnel dissection (ESTD) has shown promising preliminary efficacy for large superficial esophageal squamous cell neoplasms (SESCNs). This study reports the outcomes of both single- and double-tunnel ESTD for large SESCNs, and compares the efficiency of the two techniques for treating circumferential SESCNs.

PATIENTS AND METHODS: 46 patients with large SESCNs underwent ESTD at a single hospital between October 2011 and March 2016. Relevant clinical data were retrospectively collected and analyzed.

RESULTS: For all patients, the en bloc and R0 resection rates were 95.7 % and 82.6 %, respectively. Perforation and cardiac mucosal laceration were detected in 2.2 % (1/46) and 6.5 % (3/46) of the procedures, respectively. Postoperative stenosis occurred in 12 patients (26.1 %). Of the 18 patients with circumferential lesions, those who received a double-tunnel ESTD procedure (n = 6) underwent dissection faster than those who had a single-tunnel ESTD procedure (n = 12) (0.32 vs. 0.12 cm2/min; P = 0.02).

CONCLUSION: ESTD was effective for large SESCNs. The double-tunnel ESTD appeared to decrease operative time compared with single-tunnel ESTD for circumferential lesions.

Medienart:

E-Artikel

Erscheinungsjahr:

2018

Erschienen:

2018

Enthalten in:

Zur Gesamtaufnahme - volume:50

Enthalten in:

Endoscopy - 50(2018), 5 vom: 01. Mai, Seite 505-510

Sprache:

Englisch

Beteiligte Personen:

Zhang, Wengang [VerfasserIn]
Zhai, Yaqi [VerfasserIn]
Chai, Ningli [VerfasserIn]
Linghu, Enqiang [VerfasserIn]
Li, Huikai [VerfasserIn]
Feng, Xiuxue [VerfasserIn]

Links:

Volltext

Themen:

Journal Article

Anmerkungen:

Date Completed 03.04.2019

Date Revised 03.04.2019

published: Print-Electronic

Citation Status MEDLINE

doi:

10.1055/s-0043-122384

funding:

Förderinstitution / Projekttitel:

PPN (Katalog-ID):

NLM278858821