Comparison of sequential vaginal and sublingual misoprostol after a vaginal loading dose for second-trimester abortion
Copyright © 2017. Published by Elsevier B.V..
OBJECTIVE: To evaluate the effects of sequential vaginal and sublingual misoprostol after a vaginal loading dose for second-trimester abortion.
MATERIALS AND METHODS: From January 2006 to December 2011, 173 women received an 800-μg vaginal loading dose of misoprostol. After the loading dose, 103 patients received 800 mg of misoprostol vaginally and 70 patients received 400 mg of misoprostol sublingually every 12 h until the delivery of the fetus.
RESULTS: In the vaginal group, the average abortion time was 1.07 ± 1.29 days; that was 0.82 ± 0.66 days in the sublingual group. Sequential sublingual misoprostol after a vaginal loading dose of 800 mg with an administration interval of 12 h had a similar abortion rate and time to abortion. In addition, this protocol reduced unnecessary digital pelvic examinations and speculum examinations.
CONCLUSION: This sequential sublingual misoprostol regimen might be a suitable regimen for mid-trimester abortion.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:56 |
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| Enthalten in: |
Taiwanese journal of obstetrics & gynecology - 56(2017), 3 vom: 14. Juni, Seite 312-314 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Huang, Ming-Chao [VerfasserIn] |
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| Links: |
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| Themen: |
0E43V0BB57 |
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| Anmerkungen: |
Date Completed 11.04.2018 Date Revised 30.03.2022 published: Print Citation Status MEDLINE |
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| doi: |
10.1016/j.tjog.2017.04.008 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
NLM272794732 |
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| 100 | 1 | |a Huang, Ming-Chao |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Comparison of sequential vaginal and sublingual misoprostol after a vaginal loading dose for second-trimester abortion |
| 264 | 1 | |c 2017 | |
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a ƒaComputermedien |b c |2 rdamedia | ||
| 338 | |a ƒa Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Date Completed 11.04.2018 | ||
| 500 | |a Date Revised 30.03.2022 | ||
| 500 | |a published: Print | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a Copyright © 2017. Published by Elsevier B.V. | ||
| 520 | |a OBJECTIVE: To evaluate the effects of sequential vaginal and sublingual misoprostol after a vaginal loading dose for second-trimester abortion | ||
| 520 | |a MATERIALS AND METHODS: From January 2006 to December 2011, 173 women received an 800-μg vaginal loading dose of misoprostol. After the loading dose, 103 patients received 800 mg of misoprostol vaginally and 70 patients received 400 mg of misoprostol sublingually every 12 h until the delivery of the fetus | ||
| 520 | |a RESULTS: In the vaginal group, the average abortion time was 1.07 ± 1.29 days; that was 0.82 ± 0.66 days in the sublingual group. Sequential sublingual misoprostol after a vaginal loading dose of 800 mg with an administration interval of 12 h had a similar abortion rate and time to abortion. In addition, this protocol reduced unnecessary digital pelvic examinations and speculum examinations | ||
| 520 | |a CONCLUSION: This sequential sublingual misoprostol regimen might be a suitable regimen for mid-trimester abortion | ||
| 650 | 4 | |a Clinical Trial | |
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Abortion | |
| 650 | 4 | |a Cytotec | |
| 650 | 4 | |a Misoprostol | |
| 650 | 4 | |a Second-trimester | |
| 650 | 7 | |a Abortifacient Agents, Nonsteroidal |2 NLM | |
| 650 | 7 | |a Misoprostol |2 NLM | |
| 650 | 7 | |a 0E43V0BB57 |2 NLM | |
| 700 | 1 | |a Hsieh, Ching-Hung |e verfasserin |4 aut | |
| 700 | 1 | |a Huang, Jian-Pei |e verfasserin |4 aut | |
| 700 | 1 | |a Tsai, Hsiu-Ting |e verfasserin |4 aut | |
| 700 | 1 | |a Lee, Maw-Sheng |e verfasserin |4 aut | |
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