Randomized clinical study assessing two membranes for guided bone regeneration of peri-implant bone defects : clinical and histological outcomes at 6 months
© 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd..
PURPOSE: To test whether or not one of two membranes is superior for peri-implant-guided bone regeneration in terms of clinical and histologic outcomes.
MATERIAL AND METHODS: In 27 patients, 27 two-piece dental implants were placed in single-tooth gaps in the esthetic area. Buccal dehiscence and/or fenestration-type defects were regenerated using demineralized bovine bone mineral and randomly covered with either a resorbable membrane (RES) or a titanium-reinforced non-resorbable membrane (N-RES). Clinical measurements included vertical defect resolution and the horizontal thickness of regenerated bone at implant placement and at 6 months. Statistics were performed by means of nonparametric testing.
RESULTS: The remaining mean vertical defect measured 4 mm (±2.07) (RES) and 2.36 mm (±2.09) (N-RES) (P = 0.044) at baseline and 0.77 mm (±0.85) (RES) and 0.21 mm (±0.80) (N-RES) (P = 0.021) at re-entry. This translated into a defect resolution of 85% (RES) and 90.7% (N-RES) (P = 0.10). The horizontal thickness after augmentation measured 3.46 mm (±0.52) (RES) and 2.82 mm (±0.50) (N-RES) (P = 0.004). The mean loss in horizontal thickness from baseline to re-entry measured 2.23 mm (SD ±1.21) (RES) and 0.14 mm (±0.79) (N-RES) (P = 0.017). The horizontal changes in thickness at the implant shoulder level were statistically significant between the groups (P = 0.0001).
CONCLUSIONS: Both treatment modalities were clinically effective in regenerating bone as demonstrated by a similar horizontal thickness and vertical defect fill at 6 months. The N-RES group exhibited significantly less horizontal bone thickness reduction from baseline to follow-up.
| Medienart: |
E-Artikel |
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| Erscheinungsjahr: |
2017 |
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| Erschienen: |
2017 |
| Enthalten in: |
Zur Gesamtaufnahme - volume:28 |
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| Enthalten in: |
Clinical oral implants research - 28(2017), 10 vom: 28. Okt., Seite 1309-1317 |
| Sprache: |
Englisch |
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| Beteiligte Personen: |
Naenni, Nadja [VerfasserIn] |
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| Links: |
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| Themen: |
Alveolar ridge augmentation |
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| Anmerkungen: |
Date Completed 05.09.2018 Date Revised 08.04.2022 published: Print-Electronic Citation Status MEDLINE |
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| doi: |
10.1111/clr.12977 |
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| funding: |
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| Förderinstitution / Projekttitel: |
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| PPN (Katalog-ID): |
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| 100 | 1 | |a Naenni, Nadja |e verfasserin |4 aut | |
| 245 | 1 | 0 | |a Randomized clinical study assessing two membranes for guided bone regeneration of peri-implant bone defects |b clinical and histological outcomes at 6 months |
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| 500 | |a published: Print-Electronic | ||
| 500 | |a Citation Status MEDLINE | ||
| 520 | |a © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. | ||
| 520 | |a PURPOSE: To test whether or not one of two membranes is superior for peri-implant-guided bone regeneration in terms of clinical and histologic outcomes | ||
| 520 | |a MATERIAL AND METHODS: In 27 patients, 27 two-piece dental implants were placed in single-tooth gaps in the esthetic area. Buccal dehiscence and/or fenestration-type defects were regenerated using demineralized bovine bone mineral and randomly covered with either a resorbable membrane (RES) or a titanium-reinforced non-resorbable membrane (N-RES). Clinical measurements included vertical defect resolution and the horizontal thickness of regenerated bone at implant placement and at 6 months. Statistics were performed by means of nonparametric testing | ||
| 520 | |a RESULTS: The remaining mean vertical defect measured 4 mm (±2.07) (RES) and 2.36 mm (±2.09) (N-RES) (P = 0.044) at baseline and 0.77 mm (±0.85) (RES) and 0.21 mm (±0.80) (N-RES) (P = 0.021) at re-entry. This translated into a defect resolution of 85% (RES) and 90.7% (N-RES) (P = 0.10). The horizontal thickness after augmentation measured 3.46 mm (±0.52) (RES) and 2.82 mm (±0.50) (N-RES) (P = 0.004). The mean loss in horizontal thickness from baseline to re-entry measured 2.23 mm (SD ±1.21) (RES) and 0.14 mm (±0.79) (N-RES) (P = 0.017). The horizontal changes in thickness at the implant shoulder level were statistically significant between the groups (P = 0.0001) | ||
| 520 | |a CONCLUSIONS: Both treatment modalities were clinically effective in regenerating bone as demonstrated by a similar horizontal thickness and vertical defect fill at 6 months. The N-RES group exhibited significantly less horizontal bone thickness reduction from baseline to follow-up | ||
| 650 | 4 | |a Comparative Study | |
| 650 | 4 | |a Journal Article | |
| 650 | 4 | |a Randomized Controlled Trial | |
| 650 | 4 | |a alveolar ridge augmentation | |
| 650 | 4 | |a bone and bones | |
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| 700 | 1 | |a Schneider, David |e verfasserin |4 aut | |
| 700 | 1 | |a Jung, Ronald E |e verfasserin |4 aut | |
| 700 | 1 | |a Hüsler, Jürg |e verfasserin |4 aut | |
| 700 | 1 | |a Hämmerle, Christoph H F |e verfasserin |4 aut | |
| 700 | 1 | |a Thoma, Daniel S |e verfasserin |4 aut | |
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